Pyridium


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Pyridium

 [pĭ-rid´e-um]
trademark for preparations of phenazopyridine hydrochloride; a urinary tract analgesic.

phenazopyridine hydrochloride

AZO-Gesic, Azo-Standard, Baridium, Phenazo (CA), Prodium, Pyridium, ReAzo, UTI Relief

Pharmacologic class: Nonopioid analgesic

Therapeutic class: Urinary analgesic

Pregnancy risk category B

Action

Unknown. Thought to act locally on urinary tract mucosa to produce analgesic or anesthetic effects, relieving urinary burning, urgency, and frequency.

Availability

Tablets: 95 mg, 97.2 mg, 100 mg, 200 mg

Indications and dosages

Pain caused by lower urinary tract irritation

Adults: 200 mg P.O. t.i.d.

Children: 12 mg/kg P.O. daily in three divided doses

Contraindications

• Hypersensitivity to drug
• Renal insufficiency

Precautions

Use cautiously in:
• hepatitis
• pregnant or breastfeeding patients
• children younger than age 12.

Administration

• Give with or after meals.
• Discontinue after 2 days, as prescribed, when administering with antibiotics.

Adverse reactions

CNS: headache

EENT: contact lens staining

GI: GI disturbances

GU: bright orange urine, renal toxicity

Hepatic: hepatotoxicity

Hematologic: hemolytic anemia,

methemoglobinemia

Skin: rash, pruritus

Other: anaphylactoid-like reaction

Interactions

Drug-diagnostic tests.Bilirubin, glucose, ketones, protein, steroids: interference with urine tests based on spectrophotometry or color reactions

Patient monitoring

• Monitor patient for symptomatic improvement of urinary tract infection (UTI).
• Assess follow-up urine culture after antibiotic therapy ends.

Monitor for yellowing of skin or sclera. This change may indicate drug accumulation caused by impaired renal excretion, warranting drug withdrawal.

Patient teaching

• Explain drug therapy and measures to help prevent UTI recurrence.
• Tell patient drug may discolor urine and tears and may stain clothing and contact lenses.

Advise patient to contact pre-scriber promptly if symptoms don't improve or if skin or eyes become yellow.
• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the tests mentioned above.

Pyridium

(pī-rĭd′ē-əm)
A trademark for the drug phenazopyridine hydrochloride.

Pyridium

trademark for a urinary tract analgesic (phenazopyridine hydrochloride).

Pyridium®

Butabarbital, see there.
References in periodicals archive ?
A To my knowledge, crystals of Pyridium have not been described in urinary sediment.
Hinman identified high peri-pelvic and peri-ureteral concentrations of preoperatively administered Pyridium in the setting of iatrogenic ureteral obstruction.
Abstract: Pyridium (phenazopyridine hydrochloride) is often prescribed as an analgesic in patients following trauma, surgery, or infections of the urinary tract.
Orange: phenazopyridine (such as in Pyridium, a bladder "soother"); sulfasalazine (used to treat ulcerative colitis and other bowel problems)
nitro-furantoin + pyridium for 2-3 weeks) therapy was also discussed as a means of ruling out an infectious etiology (given that her symptoms are episodic).
Able manufactures oral solid dosage products, including generic versions of the brand Pyridium as well as suppositories at its South Plainfield, N.
2,21] In specific clinical situations, the following tests are recommended: symptoms/quality of life questionnaires (International Consultation on Incontinence Questionnaire [ICIQ] grade A, Incontinence Impact Questionnaire [IIQ]-7, Urogenital Distress Inventory [UDI]-6), pad weight testing, serum creatinine, uroflowmetry, post-void residual volume (PVR), methylene blue or pyridium pad testing, cystoscopy and urodynamic studies (UDS).
The integrity of the upper urinary tract should also be evaluated with an intravenous pyelography, a retrograde pyelography or a pyridium test.
Building on the momentum we've created, we plan to re-launch two additional branded products in women's healthcare this year, Doryx and Pyridium Plus.
The recall is limited to Centrax, Ergostat, Estrovis, Norlestrin, Norlutin, Pyridium, Norlutate and Tedral.