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pyoderma gangrenosum |
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pyoderma /pyo·der·ma/ (pi″o-der´mah) any purulent skin disease. pyoderma gangreno´sum a rapidly evolving cutaneous ulcer or ulcers, with marked undermining of the border.
pyoderma gangrenosum, a rapidly evolving, idiopathic, chronic debilitating skin disease that usually accompanies a systemic disease, especially chronic ulcerative colitis, and is characterized by irregular, boggy, blue-red ulcers with undermined borders surrounding purulent necrotic bases. pyoderma any purulent skin disease. Includes pustule, pimple, acne, impetigo and furunculosis. callus pyoderma see callus pyoderma. contagious porcine pyoderma see contagious porcine pyoderma. deep pyoderma bacterial infections involving the dermis and often subcutaneous tissues. There may be systemic illness. dry pyoderma see zinc-responsive dermatosis. fold pyoderma see fold dermatitis. pyoderma gangrenosum a rapidly evolving cutaneous ulcer or ulcers, with undermining of the border. interdigital pyoderma infection of the interdigital skin in dogs; may be associated with trauma, Demodex canis infestation, or foreign bodies such as grass seeds. juvenile pyoderma a sterile, pustular skin disease on the face and head and sometimes ears, anus and prepuce, in one or more puppies of a litter, usually around weaning age. Dachshunds, Golden retrievers and Gordon setters appear to be predisposed. There is often fever, anorexia and lymphadenopathy, particularly of submandibular lymph nodes which may form abscesses and drain, hence the alternative name of puppy strangles. Staphylococcus spp. are frequently cultured from affected skin, but the etiology of the disease is unclear. Called also juvenile cellulitis, and juvenile sterile granulomatous dermatitis and lymphadenitis. mucocutaneous pyoderma occurs on the lip margins and perioral skin of dogs; German shepherd dogs are predisposed. nasal pyoderma a deep bacterial folliculitis and furunculosis on the dorsum of the nose in dogs, particularly German shepherd dogs, Bull terriers, Collies and Pointers. Trauma may be a factor in the etiology. perianal pyoderma see perianal fistula. pressure point pyoderma see pressure points. skin-fold pyoderma see fold dermatitis. superficial pustular pyoderma see impetigo. surface pyoderma see acute moist dermatitis. tail fold pyoderma see fold dermatitis. pyoderma gangrenosum Dermatology A rare idiopathic condition characterized by skin ulceration; at least 50% of Pts have associated systemic disease, including infection, malignancy, vasculitis, collagen vascular diseases, DM, trauma Clinical
An initial bite-like lesion, pain, arthralgias and malaise; the classic ulcers occur on the legs; a superficial variant, atypical PG, tends to occur on the hands; involvement of other organ systems manifests as sterile neutrophilic abscesses in the
lungs, heart, CNS, GI tract, eyes, liver, spleen, bone, and lymph nodes Associated conditions IBD–either ulcerative colitis or Crohn's disease, a symmetric polyarthritis, hematologic disorders–eg, leukemia or preleukemia,
predominantly myelocytic, monoclonal gammopathies, especially IgA gammopathy; less common associations include arthritides–eg, psoriatic arthritis, osteoarthritis, or spondyloarthropathy; liver disease–eg, hepatitis and primary biliary
cirrhosis; myeloma–especially IgA type and immunologic diseases–eg, SLE, Sjögren's DiffDx Acute febrile neutrophilic dermatosis, aphthous stomatitis, atrophie blanche, Behçet disease, chancroid, Churg-Strauss
syndrome–allergic granulomatosis, ecthyma, ecthyma gangrenosum, herpes simplex, hypersensitivity vasculitis–leukocytoclastic vasculitis, impetigo, insect bites, sporotrichosis, SCC, venous insufficiency, verrucous carcinoma,
Wegener's granulomatosis Management Anti-inflammatories–eg, corticosteroids, immunosuppressants How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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