pure red cell aplasia

aplasia

defective development or complete absence of an organ or tissue due to failure of development.

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aplasia cutis

see epitheliogenesis imperfecta.

pure red cell aplasia

selective depression of erythropoiesis with anemia resulting.

segmental aplasia

aplasia of a segment of an organ, e.g. uterus.

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pure red cell aplasia

Hematology A type of anemia caused by selective depletion of erythroid cells

Pure red cell aplasia types

Acute Aplastic crisis A condition often preceded by viral gastroenteritis, pneumonitis, primary atypical pneumonia, mumps, viral hepatitis, pregnancy and drug toxicity Clinical Malaise, pallor and other symptoms of a chronic, compensated hemolyzing process Treatment The only effective modality is discontinuance of inculpated drug, if identified

Chronic Either 1.Congenital Diamond-Blackfan disease A condition due to a ↓ in erythrocyte stem cells with ↓ colony-forming units and burst-forming units and a poor response to erythropoietin Treatment Transfusions, corticosteroids or 2. Acquired 30-50% of chronic acquired PRCA is associated with thymoma, as well as rheumatoid arthritis, lupus erythematosus, chronic active hepatitis, hemolytic anemia and CLL