pulmonary surfactant

(redirected from Pulmonary surfactants)

pulmonary surfactant

See surfactant, def. 2.

pulmonary surfactant

A lipoprotein secreted by type II alveolar cells that decreases the surface tension of the fluid lining the alveoli, permitting expansion. Synthetic lung surfactant is available for treating patients with respiratory distress syndrome. In obstetrics, fetal production of surfactant can be stimulated by administration of a glucocorticoid 24 to 48 hr before an inevitable preterm birth.
Synonym: lung surfactant See: betamethasone; lecithin-sphingomyelin ratio
See also: surfactant
References in periodicals archive ?
Comparisons of efficacy of different pulmonary surfactants for the treatment of neonatal respiratory distress syndrome.
Objective: To analyze the therapeutic effect of pulmonary surfactant (PS) in combination with nasal continuous positive airway pressure (NCPAP) therapy on neonatal respiratory distress syndrome (NRDS).
KEY WORDS: Neonate, Pulmonary surfactant, Respiratory distress syndrome.
Study on early application of pulmonary surfactant combined with assisted ventilation in the treatment of respiratory distress syndrome in premature infants.
Clinical study on nasal continuous positive airway pressure (NCPAP) combined with pulmonary surfactant in treatment of neonatal respiratory distress syndrome.
Pulmonary surfactant and nasal continuous positive airway pressure ventilation in the treatment of neonatal respiratory distress syndrome.
Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: results of a meta-analysis.
Pulmonary surfactants function to decrease the surface tension of lung alveoli so that they remain open and functional upon exhalation.
The patent provides coverage for compositions that employ a combination of certain pulmonary surfactants with a broad array of protease inhibitors, administered as either a liquid or aerosol, for treating pulmonary inflammation, the company said.
Discovery believes that through its technology, pulmonary surfactants have the potential, for the first time, to be developed into a series of respiratory therapies for critical care and other hospitalized patients where there are few or no approved therapies available.
During this period]' his research on pulmonary surfactants further illuminated the ways in which surfactants are produced by lung cells, their importance in normal pulmonary function, and how they interact with chemicals and hormones.