pulmonary surfactant

(redirected from Pulmonary surfactants)

pulmonary surfactant

See surfactant, def. 2.

pulmonary surfactant

A lipoprotein secreted by type II alveolar cells that decreases the surface tension of the fluid lining the alveoli, permitting expansion. Synthetic lung surfactant is available for treating patients with respiratory distress syndrome. In obstetrics, fetal production of surfactant can be stimulated by administration of a glucocorticoid 24 to 48 hr before an inevitable preterm birth.
Synonym: lung surfactant See: betamethasone; lecithin-sphingomyelin ratio
See also: surfactant
References in periodicals archive ?
Pulmonary surfactants are produced naturally in the lung and are essential for normal respiratory function and survival.
Pulmonary surfactants function to decrease the surface tension of lung alveoli so that they remain open and functional upon exhalation.
Discovery believes that through its technology, pulmonary surfactants have the potential, for the first time, to be developed into a series of respiratory therapies for critical care and other hospitalized patients where there are few or no approved therapies available.
During this period]' his research on pulmonary surfactants further illuminated the ways in which surfactants are produced by lung cells, their importance in normal pulmonary function, and how they interact with chemicals and hormones.
Discovery Labs previously secured worldwide exclusive rights to the CAG technology for use with all pulmonary surfactants, alone or in combination with other pharmaceutical compounds, for a wide range of respiratory disorders.
Discovery believes that through its surfactant technology, pulmonary surfactants have the potential, for the first time, to be developed into a series of respiratory therapies for hospitalized and ambulatory patients.