Pulmonary sequestration

sequestration /se·ques·tra·tion/ (se″kwes-tra´shun)

1. the formation of a sequestrum.

2. the isolation of a patient.

3. a net increase in the quantity of blood within a limited vascular area, occurring physiologically, with forward flow persisting or not, or produced artificially by the application of tourniquets.

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pulmonary sequestration  loss of connection of lung tissue with the bronchial tree and the pulmonary veins.

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sequestration

1. abnormal separation of a part from a whole, as a portion of a bone by a pathological process, or a portion of the circulating blood in a specific part occurring naturally or produced by application of a tourniquet.

2. isolation of a patient.

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feline corneal sequestration

see corneal sequestrum.

pulmonary sequestration

loss of connection of lung tissue with the bronchial tree and the pulmonary veins.

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pulmonary sequestration

 An uncommon–1:1000 adult lobectomy specimens congenital anomaly characterized by misplaced lung parenchyma, which lacks normal communication with the main tracheobronchial tree that may be intralobar or extralobar

Pulmonary sequestration  

   Intralobar Extralobar

Separate pleura No Yes

Location  Posterior basilar Above or below diaphragm

Age of onset 50% > 20 years  60% < one year

Symptoms  Recurrent pneumonia Respiratory distress

Laterality 60% left  90% left

♂:♀ ratio 1:1 4:1

Other defects Uncommon  > 50%, eg diaphragmatic

         defects, tuberous sclerosis

Bronchial
communication Uncommon, small  None

Arterial supply  Systemic; single aorta Systemic; multiple, small

Venous drainage Inferior pulmonary Systemic; azygous and
        vein          hemiazygous vein