The levels of some pteridines
increased significantly if there is a tumour inside the body.
1): (1) enzymatic scission between the pterin and the pABA-glutamyl moieties (as also occurs during oxidative cleavage); (2) deamination of the pteridine
ring; (3) hydrolysis of the pABA-glutamyl linkage of folates or pABA-glutamate; and (4) removal of the polyglutamyl tail, leaving just the first glutamate.
Sulfonamides inhibit one of the integral enzymes in folate synthesis, dihydropteroate synthase (DHPS), which catalyzes the condensation of para-aminobenzoic acid and pteridine
to form dihydropteroic acid (Figure).
Although most reports do not refer to the problem of resistance to pteridine
, all these recognize the responsibility of plasmids with weights similar to those reported here for resistance to sulpha and trimethoprim (14-17).
This multimeric enzyme, which functions in the synthesis of pteridine
eye pigments as well as BH4 cofactor, exists as multiple isoforms that are expressed in a developmentally and functionally specific manner (O'Donnell et al.
Wing color in Pontia and related pierine species is determined by two types of pigments: white and yellow pteridine
pigments, and black melanin pigments.
Age determination in the adult screwworm (Diptera: Calliphoridae) by pteridine
both the melanins and the pteridine
compounds that generate the reds and yellows are by-products of metabolic activity that took place when the cells were still alive in the late pupa stage.
It is a book for the libraries of research institutes and universities, primarily of interest to chemists, medicinal chemists, and biochemists engaged in pteridine
Neopterin, a pteridine
derivative produced by activated macrophages in response to stimulation by interferon-[gamma], is a marker of both immune activation and coronary artery disease (CAD) activity (2).
The quantitative relations between variation in red eye pigment and related pteridine
compounds in Drosophila melanogaster.
1-4) Folate also differs from folic acid "in the extent of the reduction state of the pteroyl group, the nature of the substituents on the pteridine
ring and the number of glutamyl residues attached to the pteroyl group.