Burkholderia cepacia

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Burkholderia cepacia

a bacterial species found in rotted onions and in clinical specimens; commonly found in respiratory secretions in patients with cystic fibrosis, it is frequently resistant to many antibiotics.
Synonym(s): Pseudomonas cepacia

Burkholderia cepacia

formerly Pseudomonas cepacia. A group of bacteria found in the environment that are often resistant to common antibiotics. Immunocompromised persons or those with chronic lung disease, especially cystic fibrosis, are susceptible to infection. In patients without cystic fibrosis, B. cepacia infections are almost all nosocomial or related to IV drug abuse. Outbreaks have been related to intra-aortic balloon pumps, contaminated water sources, respiratory therapy equipment such as reusable electronic ventilator probes or contaminated disinfectants. A variety of approaches including strict segregation of cystic fibrosis patients based on the presence of this organism have been tried in order to reduce nosocomial transmission. Even a single significant nosocomial infection with B. cepacia may warrant investigation.

Burkholderia cepacia

A group of at least 17 Pseudomonas-like gram-negative bacteria found in the environment—e.g., plants, water, soil and in hospital—which may colonise the respiratory tract.

Clinical findings
May cause life-threatening pneumonia in patients with cystic fibrosis, chronic granulomatous disease and lung transplants; B cepacia may also cause urinary tract infections and infect sterile body sites.
 
Epidemiology
Transmitted by direct physical contact from contaminated environmental sources, fluids and medical devices, by aerosol or person-to-person.

Burkholderia cepacia

Pseudomonas cepacia Bacteriology A bacterium found in the environment–eg, plants, water, soil, and in hospital environment, which may colonize the respiratory tract of Pts with cystic fibrosis; transmitted by direct physical contact from contaminated environmental sources, fluids and medical devices and, by aerosol, person-to-person Clinical May cause life-threatening URIs in Pts with cystic fibrosis, chronic granulomatous disease; also associated with UTIs and may infect sterile body sites

Burk·hol·der·i·a ce·pa·ci·a

(bŭrk-hol-der'ē-ă sē-pā'shē-ă)
A bacterial species found in rotted onions and in clinical specimens; commonly found in respiratory secretions in patients with cystic fibrosis, it is frequently resistant to many antibiotics. Formerly known as Pseudomonas cepacia.
References in periodicals archive ?
Pseudomonas cepacia infection in cystic fibrosis: An emerging problem.
Roitman from Albany, California, hold a patent for the use of Pseudomonas cepacia and pyrrolnitrin.
Infection with Pseudomonas cepacia in chronic granulomatous disease: role of nonoxidative killing by neutrophils in host defense.
Intercontinental spread of a highly transmissible clone of Pseudomonas cepacia proved by multilocus enzyme electrophoresis and ribotyping.
Pseudomonas cepacia and Pseudomonas maltophilia in cystic fibrosis patients [abstract].