Pseudomonas aeruginosa


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Pseu·do·mo·nas ae·ru·gi·no·'sa

a bacterial species found in soil, water, and commonly in clinical specimens (wound infections, infected burn lesions, urinary tract infections); the causative agent of blue pus; occasionally pathogenic for plants; usually causes infections in humans in whom there is a defect in host defense mechanisms. It is the type species of the genus Pseudomonas.
Synonym(s): blue pus bacillus

Pseudomonas aeruginosa

Etymology: Gk, pseudes, false, monas, unity
a species of gram-negative, nonspore-forming, motile bacteria that may cause various human diseases ranging from purulent meningitis to nosocomial infected wounds. Also called Pseudomonas pyocyanea.

pseudomonas aeruginosa

A normal soil inhabitant and human saprobe/commensal which may contaminate various solutions and fluids in a hospital, causing opportunistic infection in immunocompromised patients.
 
Clinical findings
Infective endocarditis in IV drug users, respiratory tract infections, urinary tract infections, bacteraemia, meningitis, “malignant” external otitis.

Management
Aminoglycosides—e.g., gentamicin, amikacin, netilmicin, tobramycin, etc. 

Pathogenesis
Pseudonomas aeruginosa is both invasive and toxicogenic, and infects patients in a 3-step process:
1. Bacterial attachment and colonization—mediated by pili and antiphagocytic effects of the organism’s polysaccharide capsule;
2. Local invasion—mediated by elastase and bacterial alkaline protease; and
3. Dissemination—high-dose tobramycin delivered by aerosol is reportedly effective in patients with cystic fibrosis.

Pseudomonas aeruginosa

A normal soil inhabitant and human saprophyte that may contaminate various solutions in a hospital, causing opportunistic infection in weakened Pts Clinical Infective endocarditis in IVDAs, RTIs, UTIs, bacteremia, meningitis, 'malignant' external otitis Treatment Aminoglycosides–eg, gentamicin, amikacin, tobramycin, etc

Pseu·do·mo·nas ae·ru·gi·no·sa

(sū-dō-mōnăz ē-rū-ji-nōsă)
Bacterial species found in soil, water, and commonly in clinical specimens (wound infections, infected burn lesions, urinary tract infections); produces blue pus.
Enlarge picture
Psuedomonas Aeruginosa: infection of the distal foot

Pseudomonas aeruginosa

A species that produces a distinctive blue-green pigment, grows readily in water, and may cause life-threatening infections in humans, including nosocomial pneumonia, urinary tract infections, and sepsis. It may also cause folliculitis, malignant otitis externa, and skin infections in patients who have suffered burns. See: illustration
See also: Pseudomonas
Pseudomonas aeruginosa Gram-negative aerobic infection, with characteristic turquoise-green pus; pseudomonal infections respond to ticarcillin with clavulanic acid (Timentin)

Pseudomonas

a genus of gram-negative, strictly aerobic bacteria, some species of which are pathogenic for plants and vertebrates.

Pseudomonas aeruginosa
a common isolate from wounds, burns and urinary tract infections and from many other accumulations of pus in all species. Also commonly found in otitis externa, fleece rot in sheep, and some cases of bovine mastitis. Its presence may be indicated by a distinctive blue or green color of the pus or infected site.
Pseudomonas fluorescens
a common cause of food spoilage and a frequent isolate from wounds and other contaminated sites in animals.
Pseudomonas mallei
see burkholderia mallei.
Pseudomonas pseudomallei
see burkholderia pseudomallei.
Pseudomonas putida
causes septicemia in aquarium fish.
References in periodicals archive ?
Dissemination of a class I integron carrying VIM-2 carbapenemase in Pseudomonas aeruginosa clinical isolates from a hospital intensive care unit in Annaba, Algeria.
Aridis' product pipeline includes AR-301 anti-Staphylococcus aureus human monoclonal antibody to treat acute pneumonia; AR-101 anti-Pseudomonas aeruginosa LPS human monoclonal antibody; Panaecin(TM), a small molecule anti-infective gallium compound with broad spectrum activities against bacteria, viruses, and fungi; Aerucin(TM), a broadly reactive monoclonal antibody against Pseudomonas aeruginosa initially being developed to treat acute pneumonia; AR- 401 anti-Acinetobacter baumannii human monoclonal antibody; and AR-201 anti-RSV human monoclonal antibody.
Standard operating procedure for growing a Pseudomonas aeruginosa biofilm using the CDC biofilm reactor.
Ektima gangrenozum, Pseudomonas aeruginosa enfeksiyonlarinin iyi bilinen bir cilt bulgusudur ve genelde bagisikligi baskilanmis hastalarda gorulur.
He was known to be chronically infected with mucoid Pseudomonas aeruginosa, with baseline FEV 1 of 1.
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals.
Rhamnolipids produced by Pseudomonas aeruginosa were the most studied biosurfactants due to their potential applications in a wide variety of industries and the high levels of their production [38].
3] Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.
In order to know the susceptibility to carbapenems (imipenem and meropenem), ceftazidime and aztreonam as phenotypical indicator substrates of [beta]-lactamases, 30 strains of Pseudomonas aeruginosa (18 from animal clinical samples and 12 from non-chlorinated water) were analysed.
Pseudomonas aeruginosa is an opportunistic nonfermentive gram negative bacillus that is responsible for a wide variety of infections in humans ranging from relatively uncomplicated urinary tract infections (UTIs) to severe and life threatening infections including neonatal sepsis and chronic lung infections in patients with cystic fibrosis.
The leading pathogen responsible for morbidity and mortality among patients with cystic fibrosis (CF) is Pseudomonas aeruginosa that grows in a biofilm-mode in the airways.