pseudohypoaldosteronism

pseudohypoaldosteronism /pseu·do·hy·po·al·dos·ter·on·ism/ (-hi″po-al-dos´ter-ōn-izm)

1. a hereditary disorder of infancy characterized by severe salt and water depletion and other signs of aldosterone deficiency, although aldosterone secretion is normal or increased; causes include aldosterone receptor defects and renal dysfunction.

2. the endocrine abnormality associated with sodium-losing nephropathy, usually due to chronic pyelonephritis, seen primarily in adults.

[-hī′pōaldos′tərōn′izəm]

1 a hereditary disorder of infancy characterized by severe salt and water depletion and other signs of aldosterone deficiency, even though normal or elevated amounts of aldosterone are secreted. Causes include aldosterone receptor defects and renal dysfunction. Some affected infants outgrow the need for dietary salt supplements in early childhood.

2 the endocrine abnormality associated with sodium-losing nephropathy, usually resulting from chronic pyelonephritis, seen primarily in adults. See also Gordon's syndrome.

pseudohypoaldosteronism [soo″do-hi″po-al-dos´ter-ōn-izm]

a hereditary disorder of infancy, characterized by severe salt loss by the kidneys despite elevated secretion and urinary excretion of aldosterone; it is thought to be due to unresponsiveness of the distal renal tubule to aldosterone.

pseudohypoaldosteronism

an unresponsiveness of the distal renal tubule to aldosterone, resulting in severe loss of salt in the urine, despite elevated secretion and urinary excretion of aldosterone. An inherited disorder in humans.

pseudohypoaldosteronism

A heterogeneous group of salt wasting syndromes due to distal renal tubular insensitivity to mineralocorticoids–eg, aldosterone or due to a defect in the mineralocortioid receptor in the colonic mucosa, salivary gland, sweat glands, resulting in salt loss but normal adrenocortical and renal function, and a hyperactive renin-angiotensin system. Cf Hypoaldosteronism Types Type I Albright's hereditary osteodystrophy More common, and is almost invariably X-linked MIM 300100; AD MIM 103580 cases–designated type IA have been reported; there is inadequate cAMP response to PTH; Type II Due to inadequate end-organ response to ↑cAMP levels; affected children are short and stocky with a round facies, brachydactyly, tetany, foci of bony demineralization, osteitis fibrosa.

Mentioned in	?		References in periodicals archive	?		Medical browser	?		Full browser	?
Gordon's syndrome	Pseudohypoaldosteronism with increased sweat and saliva electrolyte values and frequent lower respiratory tract infections mimicking cystic fibrosis. Cystic fibrosis: newborn screening in America by Kleven, Daniel T.; McCudden, Christopher R.; Willis, Monte S. / Medical Laboratory Observer Mice with reduced levels of the WNK1 gene product demonstrated a medically desirable profile of low blood pressure, consistent with the observation that over-expression of this gene has been directly linked to a form of hypertension in humans, pseudohypoaldosteronism type II. Lexicon discovers gene to control high blood pressure by BIOTECH Patent News Their efforts focus on human genetic models of disease, including cystic fibrosis (CF), primary ciliary dyskinesia (PCD), and more unusual genetic disorders, such as pseudohypoaldosteronism (PHA). Illumina Signs Genotyping Services Agreement With the University of ... by Business Wire	pseudogeusia pseudoglanders pseudoglandular pseudoglandular period pseudoglioma pseudoglottis pseudogout pseudogynecomastia pseudohallucination pseudohematuria pseudohemophilia pseudohepatorenal syndrome pseudohermaphrodism pseudohermaphrodite pseudohermaphroditism pseudohernia pseudohyperaldosteronism pseudohyperinflation pseudohyperkalemia pseudohyperparathyroidism pseudohypertension pseudohypertrophic muscular dys-trophy pseudohypertrophic muscular dystrophy pseudohypertrophy pseudohypha pseudohypoaldosteronism pseudohypohyperparathyroidism pseudohyponatremia pseudohypoparathyroidism pseudohypophosphatasia pseudoicterus pseudoileus pseudoincontinence pseudoinfarct pseudoinfectious proctitis pseudoinsomnia pseudoisochromatic pseudoisochromatic plates pseudojaundice pseudojervine pseudokidney Pseudokidney Sign Pseudoletia separata pseudoleukemia pseudolipidosis pseudologia pseudologia fantastica pseudolymphoma Pseudolynchia pseudolysogeny pseudomalignancy	pseudohermaphrodite pseudohermaphrodite pseudohermaphroditic pseudohermaphroditic pseudohermaphroditism pseudohermaphroditism pseudohermaphroditism pseudohernia pseudohernia inguinalis pseudohorn cyst pseudohorn cyst pseudohorn cyst Pseudohyperaldosteronism pseudohyperinflation pseudohyperkalemia Pseudohyperkalemia, Familial, 1, due to Red Cell Leak pseudohyperparathyroidism pseudohypertension pseudohypertrophic dystrophy pseudohypertrophic dystrophy pseudohypertrophic muscular dys-trophy pseudohypertrophic muscular dystrophy pseudohypertrophic muscular dystrophy pseudohypertrophic muscular dystrophy pseudohypertrophic muscular paralysis pseudohypertrophic muscular paralysis pseudohypertrophic muscular paralysis pseudohypertrophic muscular paralysis pseudohypertrophy pseudohypha pseudohypoaldosteronism pseudohypohyperparathyroidism pseudohyponatremia pseudohypoparathyroidism pseudohypoparathyroidism pseudohypophosphatasia pseudoicterus pseudoileus Pseudoillness Pseudoillness Pseudoillness pseudoincontinence pseudoinfarct pseudoinfectious proctitis Pseudoinflammatory Fundus Dystrophy pseudoinsomnia pseudoinstruction Pseudointellectual pseudoionone Pseudois nayaur Pseudois nayaur pseudoisochromatic pseudoisochromatic pseudoisochromatic Pseudoisochromatic plate pseudoisochromatic plates pseudojaundice pseudojervine pseudokarst pseudokettle pseudokidney

Mentioned in

References in periodicals archive

Medical browser

Full browser

Gordon's syndrome

Pseudohypoaldosteronism with increased sweat and saliva electrolyte values and frequent lower respiratory tract infections mimicking cystic fibrosis.

Cystic fibrosis: newborn screening in America by Kleven, Daniel T.; McCudden, Christopher R.; Willis, Monte S. / Medical Laboratory Observer

Mice with reduced levels of the WNK1 gene product demonstrated a medically desirable profile of low blood pressure, consistent with the observation that over-expression of this gene has been directly linked to a form of hypertension in humans, pseudohypoaldosteronism type II.

Lexicon discovers gene to control high blood pressure by BIOTECH Patent News

Their efforts focus on human genetic models of disease, including cystic fibrosis (CF), primary ciliary dyskinesia (PCD), and more unusual genetic disorders, such as pseudohypoaldosteronism (PHA).

Illumina Signs Genotyping Services Agreement With the University of ... by Business Wire

pseudogeusia

pseudoglanders

pseudoglandular

pseudoglandular period