proximal tubule

(redirected from Proximal tubular)

proximal tubule

The first part of the tubular system of a nephron after the Bowman's capsule. It has convoluted and straight segments and is followed by the distal tubule.

proximal tubule

the convoluted tube between the loop of Henle and Bowman's capsule in the vertebrate kidney.

tubule

a small tube; a minute canal found in various structures or organs of the body.

collecting t's
the terminal channels of the nephrons which open on the summits of the renal papillae or renal crests.
convoluted t's
channels which follow a tortuous course. See also renal tubules (below) and tubuli contorti.
dentinal t's
minute channels in the dentine of a tooth that extend from the pulp cavity to the cement or the enamel. Called also dentinal canaliculi.
galactophorous t's
small channels for the passage of milk from the secreting cells in the mammary gland. Called also lactiferous ducts.
Henle's t's
see henle's tubules.
lactiferous t's
see lactiferous ducts.
mesonephric t's
the tubules comprising the mesonephros, or temporary kidney, of amniotes.
metanephric t's
the tubules comprising the permanent kidney of amniotes.
proximal tubule
intrarenal site for the reabsorption of most of the protein in the tubular fluid.
proximal convoluted tubule
the portion of the nephron immediately succeeding the glomerulus; susceptible to disease because of its early exposure to toxins in the glomerular filtrate.
renal t's
the minute canals made up of basement membrane and lined with epithelium, composing the substance of the kidney and secreting, reabsorbing, collecting and conducting the urine. Include proximal convoluted, the nephron loop (containing the proximal straight tubule, descending and ascending thin, and the distal straight tubules) and the distal convoluted tubules.
seminiferous t's
the tubules of the testis, in which spermatozoa develop and through which they leave the gland.
uriniferous t's
renal tubules; channels for the passage of urine.
References in periodicals archive ?
Cisplatin exerts its nephrotoxic effect mainly in the proximal tubular cells where it is preferentially accumulated5.
Moreover, the increased FGF23 markedly inhibits the action of the proximal tubular 1a-hydroxylase enzyme responsible for the conversion of calciferol to calcitriol (1,25[(OH).
The involvement of proximal tubular epithelial cells is uncommon.
Renal tubular epithelial cells (HK-2 cells, a proximal tubular cell line derived from normal kidney; CRL-2190) were purchased from ATCC and cultured at 37[degrees]C in a humidified atmosphere of 5% CO[sub]2 with Dulbecco's modified Eagle's medium (HyClone Pierce, USA) containing 10% fetal bovine serum (FBS; Invitrogen, USA) and 1% ampicillin.
Hemolytic anemia, Liver damage, Proximal tubular damage, Pulmonary hemorrhagic syndrome, Wet digestion.
High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases.
6) As glucose that is reabsorbed via SGLT-2 and SGLT-1 accumulates inside the proximal tubular cells, glucose transporter 2 (GLUT2) facilitates passive transport back into the surrounding interstitial fluid.
Extensive cytoplasmic lipid (confirmed by oil red O stains of cryostat sections) was present in cardiomyocytes, skeletal muscle cells, hepatocytes, and renal proximal tubular epithelial cells.
Oxidative stress and apoptotic changes in primary cultures of rat proximal tubular cells exposed to lead.
Cadmium is primarily toxic to the kidney, especially to the proximal tubular cells, the main site of accumulation.
Sevitt (1957) (5) described two patterns of change in renal failure after burning, distal tubular necrosis, and proximal tubular necrosis.
Supplementing with a ginger extract (50 mg/ kg) attenuated the proximal tubular damage and interstitial fibrosis in the kidneys and these effects were accompanied by improvements in hyperinsulinemia and hypertriglyceridemia," Yang et al.