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tyrosine kinase
(redirected from Protein-tyrosine kinases)

   Also found in: Wikipedia 0.01 sec.
tyrosine kinase
An enzyme intimately linked to signal transduction–ST, either as a receptor-type TK, which participates in transmembrane signaling, or as an intracellular TK, participating in ST to the nucleus; ↑ or ↓ TK activity is associated with various diseases, and alteration of TK activity at various points in its signaling pathway is of potential therapeutic interest; ↑ TK activity implicated in many CAs and other malignant and nonmalignant diseases, ASHD, psoriasis, inflammation; ↓ TK activity is linked to DM, X-linked agammaglobulinemia


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