The structure reveals the long-sought-after catalytic phi-clamp and the membrane spanning translocation channel, and supports the Brownian ratchet model for protein translocation
To determine whether these 18 AAs were sufficient for protein translocation
into the nucleus, we fused them with the GFP protein and found that in transfected 293T cells there were no differences in the distribution of this fusion protein and that of GFP, which indicated that N-terminal AAs 1-18 are not sufficient for Siva-1 nuclear localization (Figure 3B).
ATPase machinery uses proton motive force to generate ATP which, in turn, is essential for protein translocation
via OMVs (41).
The topics include DNA replication and cell cycle, central metabolism, protein translocation
into and across archaeal cytoplasmic membranes, and archaeosome vaccines.
This month, DiscoveRX, whose other products include the PathHunter line of whole cell assays for protein translocation
, introduced custom labeling and profiling service for kinases and proteases.
A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation
into epithelial cells.
Professor Tom Rapoport is Recognized for Shedding New Light on Protein Translocation
and Its Effect on Disease
The presentation cites AVN944 as a compound that has effects on rRNA inhibition and nucleolar protein translocation
Formed in 1999 as a spinout from Novo Nordisk, BioImage provides products, services and licenses for High Content Pathway Analysis based on its Redistribution technology for monitoring protein translocation
within a cell.
In these essays, many of which are classics or out of print contributors describe their work in yeast biology, covering cytoplasmic inheritance, homologous recombination, chromosome replication and segregation, transcription, translation, cell division, cell growth, differentiation, mating filamentation, meiosis and spore development, signal transduction, cytoskeleton and morphogenesis, membrane traffic, protein translocation
, ubiquitination and protein turnover, and genomics.
Several leading pharmaceutical and biotech screening groups have already adopted PathHunter based protein translocation
Some chapter topics include signaling in the arbuscular mycorrhizal symbiosis, the interplay between DNA replication and recombination in prokaryotes, diversity and evolution of protein translocation
, and yeast evolution and comparative genomics.