isoform

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isoform

One of two or more proteins coded independently by different genes, which have identical or nearly identical structures and functions.
References in periodicals archive ?
In present study heterozygous AB BLG protein isoform significantly associated with whey protein contents in both goat breeds (pless than 0.
In the search to understand these molecular processes, researchers uncovered an important new DAF-16 isoform - DAF-16d/f - that collaborates with other DAF-16 protein isoforms to regulate longevity.
Recent scientific research is revealing strong correlations between the presence and ratio of protein isoforms versus cancer diagnosis, staging and therapeutic response, with important quality of life implications to the patient and major potential cost savings for the health care system," said Jeffrey N.
However, with up to 30,000 or more protein variants in a single cell, protein isoform differentiation and measurement has been a major challenge in the development of clinical diagnostic assays," said Jeffrey N.
Despite the fact that alternative splicing substantially increases the diversity of this locus, most of these putative protein isoforms have not been isolated, with the exception of a few proteins encoded by KLK2 and KLK3 variants (22).
Inhibition of interactions and interconversions of prion protein isoforms by peptide fragments from the C-terminal folded domain.
Both specimens that demonstrated an expression of the 39-kDa cTnT protein isoform using MAb M7 showed expression of cTnT mRNA.
The protein isoform expressed in embryonic cardiac and skeletal muscle cells is unique to this developmental stage [5].
Since these OCT4 variants seem to be important in cancer cells and also, most of them generate the same protein isoforms, it was decided to evaluate 5'-UTR sequences of known OCT4B group variants in bladder cancer cell line of 5637 that expresses most of OCT4 transcripts.
M2 PHARMA-April 10, 2017-MetaStat Presents Supporting Data for Role of Mena Protein Isoforms in Tumor Dissemination
TF is expressed in 2 naturally occurring protein isoforms, membrane-bound full-length (fl)TF and soluble alternatively spliced (as)TF.
The book summarizes his years of research into the role of the three mammalian transforming growth factor-beta protein isoforms in bone formation.

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