X-ray crystallography

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crystallography

 [kris″tah-log´rah-fe]
the science dealing with the study of crystals.
x-ray crystallography the determination of the three-dimensional structure of molecules by means of diffraction patterns produced by x-rays of crystals of the molecules.

X-ray crystallography

a powerful technique for determining the structure of crystalline substances by measuring the diffraction patterns produced when a beam of X-rays is passed through the crystal. X-ray crystallography has provided information on the 3-D structure of PROTEINS, NUCLEIC ACIDS, DRUGS, HORMONES, VITAMINS and so on, from which atomic models can be built. Knowledge of the structure of such molecules has provided insight into how they function, and is useful in PROTEIN ENGINEERING.

crystallography

the science dealing with the study of crystals.

x-ray crystallography
the determination of the three-dimensional structure of molecules by means of diffraction patterns produced by x-rays.
References in periodicals archive ?
Dorothy Hodgkin: Biochemist and Developer of Protein Crystallography summarizes the innovative work of this Nobel Prize winner.
The successful automation of crystallization using robots such as TTP labtech's mosquito Crystal and LCP has significantly improved the process of protein crystallography and facilitates high-throughput drug discovery.
This free-electron laser produces pulses of hard X-rays a billion times brighter than the synchrotron X-rays used in traditional protein crystallography.
He covers the basic principles and main applications of nanobiotechnology as an emerging field, including the status of new materials by organic and biological nanotechnology and their applications, nanoscale probes, and applications in science and health in the areas of protein crystallography, medicine, genomics, proteomics, cell science, mechanics, optics, and magnetism.
Using protein crystallography, a 3D structure of the enzyme in complex with one of the inhibitors was solved providing guidelines for further drug improvement.
Protein crystallography string theory and RPGs: these are the things that give girl geeks an adrenaline rush.
Fluidgm's first product, introduced in 2002, was the TOPAZ system for protein crystallography employing automated free interface diffusion.
The technique involves utilising computer software already used by protein crystallography researchers in their research.
The final step in protein crystallography is model building, or determining coordinates of atoms from an electron density map.
The protein crystallography beamline will determine the structure of biological macromolecules, the function of proteins, and the molecular interactions of potential pharmaceuticals to develop improved drugs.
Effective immediately, Bruker AXS will become the worldwide distributor for Discovery Partners' Crystal Farm(TM) line of protein crystallography products.
The articles cover a broad spectrum of topics including high-pressure crystallography, magnetic structure determinations, quasi-crystals, novel biomaterials, biological minerals, structure determination via neutron and x-ray diffraction, reduced cells, standard reference materials, phase equilibria and ceramic oxides, crystallographic texture, zeolitic materials, near perfect crystals, electron diffraction, crystallographic databases, protein crystallography, crystallography in construction, and synchrotron radiation.