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propofol |
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propofol /pro·po·fol/ (pro´pah-fol) a short-acting sedative and hypnotic used as a general anesthetic and adjunct to anesthesia. propofol [pro′pah-fol] a short-acting sedative and hypnotic used as a general anesthetic and adjunct to anesthesia, administered intravenously. propofol (prō´pōfol), n brand name: Diprivan; drug class: general anesthetic; action: produces dose-dependent central nervous system depression; mechanism of action is unknown; use: induction or maintenance of anesthesia as part of a balanced anesthetic technique. propofol a rapidly acting, short duration, intravenous hypnotic anesthetic induction agent, which has low excitatory effect. It is harmless when injected into tissues or intra-arterially. The active ingredient is 2,6-di-isopropylphenol. propofol Diprivan® Anesthesiology A versatile nonopioid inhalation sedative-hypnotic with rapid–< 45 secs onset, used to induce and maintain anesthesia, and possibly control refractory status epilepticus; it ↓
intracranial and intraocular pressure, cerebral blood flow, and O2 consumption Pros Ideal for conscious sedation; useful for critically ill Pts; can be combined with other agents–eg, volatile anesthetics, NO2, opiates or
benzodiazepines; little post-op N&V Adverse effects Profound respiratory depression ± transient apnea; injection site pain, hypotension Indications Short procedures or outpatient surgery Contraindications Hemodynamically unstable Pts. Cf
Meyer-Overton rule. Cf Inhalation anesthetic, Opioid anesthetic. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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