Propecia


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Related to Propecia: Rogaine, minoxidil

finasteride

Propecia, Proscar

Pharmacologic class: Androgen inhibitor

Therapeutic class: Sex hormone, hair regrowth stimulant

Pregnancy risk category X

Action

Suppresses dihydrotestosterone levels by inhibiting the hepatic enzyme 5-alpha reductase, which converts testosterone to dihydrotestosterone in prostate, liver, and skin

Availability

Tablets: 1 mg (Propecia), 5 mg (Proscar)

Indications and dosages

Symptomatic benign prostatic hypertrophy (BPH)

Adults: 5 mg P.O. daily

To reduce risk of progression of BPH symptoms

Adults: 5 mg P.O. daily (Proscar) given with doxazosin

Male-pattern baldness

Adults: 1 mg P.O. daily

Off-label uses

• Acne in women
• Hirsutism

Contraindications

• Hypersensitivity to drug or its components
• Pregnant patients, women who may potentially be pregnant

Precautions

Use cautiously in:
• hepatic impairment, obstructive uropathy, increased risk of high-grade prostate cancer, decrease in serum prostate-specific antigen (PSA) level
• women (not indicated)
• children (not indicated).

Administration

• Give with or without food.
• Know that female patients who are or may be pregnant shouldn't handle crushed or broken tablets. (Tablets are coated, so handling of intact tablets doesn't pose a problem.)

Adverse reactions

CNS: dizziness, headache, asthenia

EENT: lip swelling

GU: erectile dysfunction, decreased ejaculate volume, decreased libido, testicular pain, gynecomastia

Musculoskeletal: back pain

Skin: rash

Interactions

Drug-drug.Theophylline: increased theophylline clearance

Drug-diagnostic tests.PSA: 50% decrease

Patient monitoring

• Carefully evaluate sustained PSA increases during therapy.
• Monitor fluid intake and output closely.

Patient teaching

• Tell patient he may take drug with or without food.
• Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness.
• Inform patient that he may experience erectile dysfunction and decreased ejaculate. Advise him to discuss these issues with prescriber.
• Caution female caregiver or companion who is or may be pregnant not to handle crushed or broken tablets.
• Tell patient he may need at least 6 months of therapy for BPH treatment and at least 3 months to see improvement in male-pattern baldness.
• Inform patient with BPH that he'll undergo periodic digital rectal exams.
• Instruct patient not to donate blood for at least 1 month after last dose.
• As appropriate, review all other significant adverse reactions and interactions, especially those related to the drugs and tests mentioned above.

Propecia

(prə-pē′shə)
A trademark for the drug finasteride.

Propecia®

Finasteride Esthetic medicine An agent for treating male pattern hair loss–androgenetic alopecia on the vertex and the anterior midscalp area Contraindications ♀, children. See Male-pattern baldness.

Propecia

A brand name for FINASTERIDE.

Patient discussion about Propecia

Q. i wan't to know. what are the side effects of propecia pills. and more about them please

A. my dad took it.. it helped a bit- but not too much. as i recall the side effects his prescribing Dr. was worried about were allergic reactions (skin rash, problem breathing, edema). but he said it can cause impotence and even breast cancer at men! he told him to check his breast for lumps every now and then.

Q. Do you know if Propecia can truly stop hair loss and even grow back hair. do you have any statistics about it? do you know if there are any side effects to this medication?

A. it does work but there is some side affects, as in E.D. while you are on the med.

More discussions about Propecia
References in periodicals archive ?
THE STATS Age: 71 Height: 6ft 3in Weight: 239lb (17 stone) Blood pressure: 122/74 Cholesterol: 223 (high) Hair: Takes Propecia.
The two major brands of the alopecia (hair loss) products are Rogaine and Propecia.
District Court for the Southern District of California, by the surviving spouse and two children of decedent John Pfaff, alleges that Propecia has known risks of depression and suicidal ideation, behavior and risk, but since the drug s inception in 1997 through 2010, Merck never included a warning about either risk on the Propecia label or in literature distributed with the drug.
It offers information and you can buy Propecia online.
Propecia works by inhibiting the activity of the enzyme 5-alpha-reductase, which stops the conversion of testosterone into dihydrotesto-sterone (DHT).
Propecia (finasteride), which began as a stronger-dose drug to treat enlarged prostates, has been prescribed to treat men with male pattern hair loss since 1997; Botox -- botulinum toxin -- first used to calm spastic eye muscles, was approved to treat frown lines in 2002; and Latisse, initially used to treat glaucoma in the 1990s, became available in 2009 for cosmetic purposes after patients noticed they were also growing longer, thicker eyelashes.
In May 2009 he was said to be using a scalp lotion with drug Propecia to try to block hair loss hormones.
Finasteride, marketed as Propecia, prevents the conversion of testosterone to a form that promotes baldness.
catid=267890764 melasma generic propecia http://www.
Romario claims he was using finasteride to treat hair loss and although it is the active ingredient in anti-baldness drug Propecia, the drug is banned by the World Anti-Doping Code because it can mask the use of steroids.
In other news, the Los Angeles Times reported that the hair-loss drug Propecia interferes with prostate-cancer testing by lowering PSA levels and masking the presence of the disease.