propafenone /pro·pa·fe·none/ (pro″pah-fe´nōn) a sodium channel blocking agent acting on the Purkinje fibers and the myocardium; used as the hydrochloride salt as an antiarrhythmic.
propafenone (prō´p
fē´nōn),
propafenone
propafenone (prō´p
fē´nōn),n brand name: Rythmol;
drug class: antidysrhythmic (Class IC);
action: able to slow conduction velocity; reduces cardiac muscle membrane responsiveness; inhibits automaticity; increases ratio of effective refractory period to action potential duration; β-blocking activity;
use: documented life-threatening dysrhythmias.
drug class: antidysrhythmic (Class IC);
action: able to slow conduction velocity; reduces cardiac muscle membrane responsiveness; inhibits automaticity; increases ratio of effective refractory period to action potential duration; β-blocking activity;
use: documented life-threatening dysrhythmias.
propafenone
Rythmol® Cardiology A beta-blocking antiarrhythmic for severe ventricular and supraventricular arrhythmias–A Fib, V Tach, conduction block, HTN Complications Ventricular proarrhythmia; conduction defects Adverse effects
Neurologic–headache, dizziness, paresthesias, peripheral neuropathy, GI–eg, N&V, anorexia. See Antiarrhythmic, Beta-blockers.
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