hematopoietic stem cell

(redirected from Prolymphocytic)
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hematopoietic stem cell

an actively dividing cell that is capable of self-renewal and of differentiation into any blood cell lineage.

hematopoietic stem cell

A progenitor cell in the bone marrow that can replicate itself as well as produce precursor cells of the various blood cell lineages.
See also: cell

Hematopoietic stem cell

A cell that can develop into any type of specialized blood cell.
References in periodicals archive ?
Prolymphocytic leukemia (PLL) is a rare and aggressive type of chronic lymphoproliferative disorder of the B- and T-cell subtype that together account for around 2% of all mature lymphoid leukemias.
An antigen defined by an antibody developed at Flinders Medical Center in Australia, FMC7, is another marker that is typically not expressed in CLL but reportedly correlates with prolymphocytic transformation.
High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H.
The two additional indications are for treatment of chronic lymphocytic leukemia (CLL) and related leukemias to include prolymphocytic leukemia, adult T-cell leukemia, and hairy cell leukemia; and for treatment of acute lymphoblastic leukemia (ALL).
IgVH genes mutation and usage, ZAP-70 and CD38 expression provide new insights on B-cell prolymphocytic leukemia (B-PLL).
Food and Drug Administration for three indications: T-cell non-Hodgkin's lymphoma, including CTCL; chronic lymphocytic leukemia (CLL) and related leukemias including prolymphocytic leukemia, adult T-cell leukemia, and hairy cell leukemia; and for treatment of acute lymphoblastic leukemia (ALL).
New Data on Activity of GRN163L in T-cell Prolymphocytic Leukemia Cells
Similar patterns of V[kappa] gene usage but different degrees of somatic mutation in hairy cell leukemia, prolymphocytic leukemia, Waldenstrom's macroglobulinemia, and myeloma.
Clinical history and histologic, immunophenotypic, viral, and cytogenetic analysis all contribute to diagnosing specific subtypes of lymphoma, including T-cell prolymphocytic leukemia, angioimmunoblastic-type peripheral T-cell lymphoma, and T-cell ALCL.
The blood samples with abnormal results included various clinical conditions, such as acute myeloid leukemia, acute lymphoblastic leukemia/lymphoma, myelodysplastic syndrome, myeloproliferative neoplasms, chronic lymphocytic leukemia, other mature B-cell lymphomas, plasma cell neoplasms, T-cell prolymphocytic leukemia, infections, chronic inflammatory conditions, leukopenia, and anemia (Table 1).
The SLL/CLL includes 2 cases with either prolymphocytic or large cell transformation.