prolymphocyte

(redirected from Prolymphocytes)

prolymphocyte

 [pro-lim´fo-sīt]
a cell of the lymphocytic series intermediate between the lymphoblast and the lymphocyte.

prolymphocyte

/pro·lym·pho·cyte/ (pro-lim´fo-sīt) a developmental form in the lymphocytic series, intermediate between the lymphoblast and lymphocyte.

prolymphocyte

Hematology A large lymphocyte- 'wannabe' not normally found in the peripheral circulation which has a high–5:1 to 3:1–N:C ratio; the centrally placed, round, ovoid or slightly indented nucleus has minimal coarse chromatin clumps along the margin, indistinct parachromatin, a large, round bluish nucleolus; organelles are indistinct; cytoplasm is medium to deep homogeneous blue and greater in prolymphocytes than in lymphoblasts or mature lymphocytes. Cf Little blue cell, Lymphoblast.

prolymphocyte

a cell of the lymphocytic series intermediate between the lymphoblast and lymphocyte.
References in periodicals archive ?
The key morphologic feature in the diagnosis of T-PLL is a population of prolymphocytes in the peripheral blood.
The bone marrow is diffusely infiltrated by prolymphocytes in most cases with variable residual hematopoiesis.
In the late 1990s, various groups reported a correlation between clinical outcome and Rai stage with respect to the morphology of CLL lymphocytes, the pattern ofbone marrowinfiltration, lymphocyte doubling time, and the percentage of prolymphocytes.
For CLL samples, the CBC report needs to include both the lymphocyte count and lymphocyte morphologic features, such as the presence of prolymphocytes, atypical lymphocytes, or smudge cells.
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a neoplasm of small, round, mature B lymphocytes, often admixed with prolymphocytes and paraimmunoblasts.
Microscopically, the lymph node architecture was partially effaced by an interfollicular proliferation of round lymphoid cells with scattered prolymphocytes (Figure 1).
A diagnosis of full blown PLL is usually associated with more than 55% circulating prolymphocytes.
For example, drying artifact can result in shrinkage and result in prolymphocytes resembling CLL cells.
34] The cells had morphologic features highly characteristic of prolymphocytes, that is, intermediate-sized lymphoid cells with a single prominent nucleolus.
The cells in MCL-P and the prolymphocytic mantle cell leukemia clearly had morphologic features of prolymphocytes.