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prolymphocyte

   Also found in: Wikipedia 0.01 sec.
prolymphocyte /pro·lym·pho·cyte/ (pro-lim´fo-sīt) a developmental form in the lymphocytic series, intermediate between the lymphoblast and lymphocyte.
prolymphocyte [pro-lim´fo-sīt]
a cell of the lymphocytic series intermediate between the lymphoblast and the lymphocyte.
prolymphocyte
a cell of the lymphocytic series intermediate between the lymphoblast and lymphocyte.
prolymphocyte
Hematology A large lymphocyte- 'wannabe' not normally found in the peripheral circulation which has a high–5:1 to 3:1–N:C ratio; the centrally placed, round, ovoid or slightly indented nucleus has minimal coarse chromatin clumps along the margin, indistinct parachromatin, a large, round bluish nucleolus; organelles are indistinct; cytoplasm is medium to deep homogeneous blue and greater in prolymphocytes than in lymphoblasts or mature lymphocytes. Cf Little blue cell, Lymphoblast.
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For CLL samples, the CBC report needs to include both the lymphocyte count and lymphocyte morphologic features, such as the presence of prolymphocytes, atypical lymphocytes, or smudge cells.
Reporting smudge cells in CLL by Siechen, Kathleen / Medical Laboratory Observer
B-Cell Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia at Extranodal Sites Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a neoplasm of small, round, mature B lymphocytes, often admixed with prolymphocytes and paraimmunoblasts.
Small lymphoid proliferations in extranodal locations by Rao, Dinesh S.; Said, Jonathan W. / Archives of Pathology & Laboratory Medicine
Microscopically, the lymph node architecture was partially effaced by an interfollicular proliferation of round lymphoid cells with scattered prolymphocytes (Figure 1).
Low-Grade B-Cell Lymphoma With Coexpression of Both CD5 and CD10: A ... by Barekman, C. L.; Aguilera, N. S. I.; Abbondazo, S. L. / Archives of Pathology & Laboratory Medicine
 
 
 
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