calcinosis cutis

(redirected from Proflichet’s disease)

cal·ci·no·sis cu·'tis

a deposit of calcium in the skin; usually occurs secondary to a preexisting inflammatory, degenerative, or neoplastic dermatosis, and is frequently seen in scleroderma. See: metastatic calcification.

calcinosis cutis

A condition characterised by circumscribed subcutaneous deposition of calcium, which may occur in a background of chronic inflammation, e.g., in connective tissue diseases, including scleroderma and systemic lupus eythematosus.
Intralesional steroid injection; etidronate disodium, a diphosphonate, may inhibit biomineralisation; surgery is of questionable efficacy.

calcinosis cutis

Dermatology Circumscribed subcutanous deposition of calcium, which may occur in a background of chronic inflammation–eg, in connective tissue diseases–eg, scleroderma, SLE Management Medical; intralesional steroid injection; etidronate disodium, a diphosphonate, may inhibit biomineralization; surgery is of questionable efficacy


Georges Charles, French physician, 1873–.
Profichet syndrome - calcareous deposits, primarily affecting extremities. Synonym(s): calcinosis circumscripta; calcinosis cutis


a condition characterized by abnormal deposition of calcium salts in the tissues.

calcinosis circumscripta
localized deposition of calcium in small nodules in subcutaneous tissues, tongue or attached to tendons or joint capsules. Called also tumoral calcinosis.
calcinosis cutis
cutaneous mineralization, a characteristic lesion in dogs with hyperadrenocorticism. Lesions are commonest on the dorsal midline, ventral abdomen and inguinal region. The skin is usually thin and atrophic.
Enlarge picture
Calcinosis cutis in a dog with Cushing's syndrome.
enzootic calcinosis
calcinosis occurring in larger numbers of animals in a local population than chance warrants. Usually a plant poisoning. May be caused by the following calcinogenic plants: solanummalacoxylon, S. linneanum,cestrumdiurnum,nierembergia veitchii and trisetum flavescens. Manifested clinically by chronic wasting, reluctance to walk and constant shifting of weight from limb to limb. Called also enteque seco.
multicentric periarticular calcinosis
described in Hungarian vizsla dogs in association with a renal tubular defect in phosphorus transport, causing progressive lameness.
pulmonary calcinosis
tumoral calcinosis
circumscribed, hard swellings with a granular radiopacity, usually immovable and located in horses on the lateral aspect of the proximal tibia.
calcinosis universalis
widespread deposition of calcium in nodules or plaques in the dermis, panniculus and muscles.