LMNA

(redirected from Pro1)

LMNA

A gene on chromosome 1q22 that encodes lamin A/C, a protein highly conserved in evolution that forms part of the two-dimensional matrix of proteins located next to the inner nuclear membrane. Lamins are involved in providing nuclear stability and chromatin structure, and in gene expression.

Molecular pathology
LMNA mutations cause the so-called laminopathies—e.g., Charcot-Marie-Tooth disease type 2B1, progeria (Hutchinson-Gilford syndrome), dilated cardiomyopathy, Emery-Dreifuss muscular dystrophy type 2, familial partial lipodystrophy, limb-girdle muscular dystrophy type 1B, mandibuloacral dysplasia, and some cases of Werner syndrome.
References in periodicals archive ?
2': PRO1 did not induce significant changes in the protein expression of PRO2_PRO3.
They know from earlier research they had done to find out if there was another product out there like their pro1 posed one that a patent is an important part of any proposed product.
Mental Space Narrator Event Narrator Eye Gaze Aud Down ctr Aud Face Behavior Neutral Brows furrowed - Neutral Teeth clenched Gloss PLUS CL: gun at Gesture: sides of body 5hs: "ooo" Mental Space Event Interpreter Interpreter/Event Eye Gaze Left down Aud -- lft dwn Face Behavior Brows furrowed -- Neutral Mouth open -- Gloss ORDER CL: 2hs lay Pro1 SAY on floor
As detailed in Table 1, PRO1 included a C-Leg, tube adapter (Otto Bock), C-Walk foot (model 1C40, Otto Bock), and hard running shoe.
The GunSport PRO1 allows natural or enhanced hearing until a blast occurs.
In its purest form, pro1 ject management separates the management function of a project from the design and execution functions.
there arrived (last night) three men1 [without PRO1 identifying themselves]
The Senate will vote tomorrow on the pact, which pro1, ides for a transfer of the waterway to Panama by the year 2000.
Mike Hagans at Clear Channel Satellite Services explains, "The new (Ku Band) carrier allows the same inexpensive Pro1 and Pro4 XDS receivers to receive programming using a much smaller dish.
Canon today unfurled the new top-of-the-line PowerShot digital camera, the new PowerShot Pro1 digital camera.
Canon's Line-Leading Eight Megapixel PowerShot Pro1 Digital Camera Premieres With a Fast 28 -- 200mm L-Series Lens