LMNA

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LMNA

A gene on chromosome 1q22 that encodes lamin A/C, a protein highly conserved in evolution that forms part of the two-dimensional matrix of proteins located next to the inner nuclear membrane. Lamins are involved in providing nuclear stability and chromatin structure, and in gene expression.

Molecular pathology
LMNA mutations cause the so-called laminopathies—e.g., Charcot-Marie-Tooth disease type 2B1, progeria (Hutchinson-Gilford syndrome), dilated cardiomyopathy, Emery-Dreifuss muscular dystrophy type 2, familial partial lipodystrophy, limb-girdle muscular dystrophy type 1B, mandibuloacral dysplasia, and some cases of Werner syndrome.
References in periodicals archive ?
At any rate, I encourage your support to the Philippine National Police, especially in our campaign against illegal gambling and report any legal activities through our PRO1 hotlines (072)-700-0518, (0917)8407783/(0920)9686779.
Alexander Pardo, PRO-1chaplain, said the first procession of the Black Nazarene in San Fernando City, La Union was made possibler with the support and initiative of Chief Superintendent Romulo Sapitula, the newly-installed regional director of PRO1.
The project management mission is broken down into a firm section relating to sports facilities (Partial DIAG Missions (state of play with records of existing ones), APS Global and APD Global, as well as PRO1 missions with quantitative metrics, ACT1, VISA1, DET1, AOR1 for the 1 st tranche of works) and an optional tranche.
For example, the Corporate Entrepreneurship indicators were represented by the variables PRO1, PRO2 and PRO3 gathered under DPRO; the INO1 variables, INO2 and INO3, were gathered under DINO; and the ASS1 variables, ASS2 and ASS3, were gathered under DASS.
Users can take advantage of Windows 10 Pro1 and the rich features of ISV certified AMD FirePro 3D graphics with 2GB of video memory designed to work with all professional applications on the HP ZBook 15u Mobile Workstation.
Os tratamentos consistiram de: PRO1 - peixes cultivados em agua tratada; RO2 - peixes cultivados em agua residuaria,; PRO3 - peixes cultivados em agua residuaria + probiotico adicionado na racao.
A: PROl GRUPO PRO1 YA SENTARSE-EN-EL-AUTO(2m) COMPLETO IRSE MANEJAR++ LEJOS(intens) TOMAR-MATE CONVERSAR QUE PENSAR TEMA IMPORTANTE GUSTAR GRANDE MEDIANO CHICO NO-IMPORTAR++ [.
2': PRO1 did not induce significant changes in the protein expression of PRO2_PRO3.
Is the PMD Pro1 Guide going to the right direction?
They know from earlier research they had done to find out if there was another product out there like their pro1 posed one that a patent is an important part of any proposed product.
A altura do SCM foi determinada por meio de uma plataforma de contato (Jump System Pro1.