primary tumor


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primary tumor

A neoplasm which, in clinical parlance, is regarded as malignant, arising in one site and capable of giving rise to metastatic or secondary tumors. See Metastasis. Cf Tumor of unknown origin.

primary tumor

In a patient with metastatic cancer, the lesion assumed to be the source of the metastases.
See also: tumor
References in periodicals archive ?
Many researchers believe killing cancer stem cells in a primary tumor should eliminate it by removing its renewable source of cancer cells, while also preventing the genesis of new cancers.
By doing this, we were able to develop a unique therapeutic that directly targets metastasis, not the growth of the primary tumor.
The purpose of this study was to compare the expression of XPA in the primary tumors and metastatic lymph nodes of 21 lung cancer patients.
Most rectal adenocarcinoma cases had identical somatic mutations in the primary tumor and the metastatic tissue (13 of 16, 81%).
In contrast, early-stage metastases and cancer cells traveling through the blood expressed genes typically active in mammary stem cells and quite distinct from primary tumor cells.
In conclusion, patients with head or neck squamous cell carcinomas shown that the esophagus, gastric carcinoma is the site with the highest risk of developing a synchronous second primary tumor in patients with head or neck carcinoma, particularly those with laryngeal carcinoma.
CTC, corresponding primary tumor tissue (FFPE) was available in 77 cases and subjected to comparative immunohistochemical ERCC1 detection.
Although some patients with thick primary tumors (thicker than 3.
Patient and methods: This cross sectional study was conducted from December 2009 to December 2011 at The Aga Khan University Hospital on patients diagnosed as having biopsy proven CUP defined by the presence of metastatic disease with no identified primary tumor at presentation.
Seventeen women had Scarf-Bloom-Richardson (SBR) grade I; 32 had SBR grade II; and 54 had SBR grade III (13-16) and were evaluated using the Automated Cellular Imaging System (ACIS) for Ki-67 expression in primary tumor and lymph nodes.
According to the company, lymphatic mapping is a procedure in which lymph nodes, that may contain tumor metastases, are identified and biopsied to determine if cancer has spread beyond the primary tumor.
The key aspect of this approach is that the stimulated immune system attacks not only the primary tumor, but also metastases located anywhere in the body.