Merkel cell tumor

(redirected from Primary Neuroendocrine Carcinoma of the Skin)
Also found in: Acronyms.

Mer·kel cell tu·mor

(mĕr'kĕl),
a rare malignant cutaneous tumor seen in sun-exposed skin of elderly patients composed of dermal nodules of small round cells with scanty cytoplasm in a trabecular pattern; the tumor cells contain cytoplasmic dense core granules resembling neurosecretory granules seen in Merkel cells.

Merkel,

Friedrich Sigmund, German anatomist and physiologist, 1845-1919.
Merkel cell tumor - a rare malignant cutaneous tumor. Synonym(s): primary neuroendocrine carcinoma of the skin; trabecular carcinoma
Merkel corpuscle - a specialized tactile sensory nerve ending in the epidermis. Synonym(s): Merkel tactile cell; Merkel tactile disk; tactile meniscus
Merkel tactile cell - Synonym(s): Merkel corpuscle
Merkel tactile disk - Synonym(s): Merkel corpuscle

Merkel cell, Merkel disk

found in the basal layer of the epidermis; believed to act as slow-acting tactile endorgans.

Merkel cell tumor
see neuroendocrine cell tumor.
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