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High-resolution approaches to studying presynaptic vesicle dynamics using variants of FRAP and electron microscopy
The neurotransmitter molecules released from the presynaptic vesicles traverse the synaptic gap and bind to proteins, termed neurotransmitter receptors, on the surface membrane of the postsynaptic neuron.
At most excitatory synapses, glutamate released from presynaptic vesicles crosses the synapse and binds to AMPA-type glutamate receptors.