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preleukemia

   Also found in: Wikipedia 0.06 sec.
preleukemia /pre·leu·ke·mia/ (pre″loo-ke´me-ah) myelodysplastic syndrome.preleuke´mic
preleukemia
a stage of bone marrow dysfunction which may progress to the development of granulocytic leukemia. It occurs in cats which in most cases are infected by feline leukemia virus. The disease is also called subleukemic granulocytic leukemia.

preleukemia
Myelodysplastic syndrome, smoldering leukemia Any of a heterogeneous group of clonal expansions of stem cells, characterized by dysmyelopoiesis–a complex of structural and functional defects–eg, abnormal cell morphology, ineffective hematopoiesis, chromosome defects–eg, aneuploidy and pseudodiploidy Examples Acquired idiopathic sideroblastic and nonsideroblastic anemias, pancytopenia with hypercellular marrow, paroxysmal nocturnal hemoglobinuria, which may all progress to ANLL


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