heterogeneous nuclear RNA

(redirected from Precursor mRNA)
Also found in: Wikipedia.

het·er·o·ge·ne·ous nuclear RNA (hnRNA),

a mixture of RNA, of high molecular weight, that never leaves the nucleus; has a high rate of turnover and consists of mRNA containign both introns and exons of genes.
Mentioned in ?
References in periodicals archive ?
MGF mRNA is derived from the IGF-I gene by alternative precursor mRNA splicing, the sequence of which has a 49-base pair insertion in humans (Hameed et al.
The spliceosome must clip these sequences, known as introns, at the right place in the precursor mRNA.
By inactivating the precursor mRNA, Bcl-2 production is thus halted, and cancer cells then become markedly sensitized to the killing effects of cancer therapy.
Alternative splicing (AS) is the process by which different exons are selected in precursor mRNAs to generate multiple protein products.