pranlukast

(redirected from Pranlukast hydrate)

pranlukast

Singulair® Allergy medicine An antileukotriene that ↓ early and late response inflammation and bronchoconstriction of asthma Effect Improved FEV1, peak expiratory flow rate, Sx–eg, night awakening, ↓ use of β2 agonists Mechanism LTD4 receptor antagonism; pranlukast is used for asthma prophylaxis; it ↓ bronchial hyperresponsiveness in chronic asthma Adverse effects Zafirkulast ↑ in PT in Pts on warfarin. See Antileukotrienes, Asthma.