postgastrectomy syndrome

(redirected from Postgastrectomy syndromes)

dump·ing syn·drome

the syndrome that occurs after eating, most often seen in patients with shunts of the upper alimentary canal that bypass or remove the pylorus; characterized by flushing, sweating, dizziness, weakness, and vasomotor collapse, resulting from rapid passage of large amounts of food into the small intestine, with an osmotic effect removing fluid from plasma and causing relative hypovolemia.

postgastrectomy syndrome

(pōst′gă-strĕk′tə-mē)

postgastrectomy syndrome

Dumping syndrome(s) GI disease A condition seen in ± 20% of those subjected to gastric surgery–eg, resection, gastroenterostomy with total gastric vagotomy and gastric bypass, especially, pyloric ablation and bypass Clinical Diaphoresis, palpitations, abdominal colic, diarrhea, due to rapid movement or dumping of gastric contents into the small intestine; PGSs occur shortly after a meal–early dumping or several hrs later–late dumping. See Intestinal overgrowth.
Postgastrectomy syndromes
Early dumping syndrome A condition affecting 5-10% of Pts with sub-total gastrectomies, due to the release of vasoactive substances–eg, serotonin, bradykinin, glucagon Clinical Onset 20-30 mins after meals with early satiety, upper GI discomfort and vasomotor phenomena–flushing, diaphoresis, palpitations, tachycardia, hypotension, resolving in one hr, weakness, N & V, diarrhea, cramping and borborygmi, flatulence, aerophagia, anemia; when prolonged malabsorption, steatorrhea, weight loss and osteomalacia  Lab ↑ Glucose–worse Sx with high carbohydrate meals, ↑ Hct, ↓ blood volume, related to dehydration, ↓ serum K+
Late dumping syndrome Less common; more polymorphous clinically; most Sx are due to reactive postcibal hypoglycemia, as the rapid entry of glucose releases GIP–gastroactive intestinal polypeptide, inhibiting the hyperglycemic response to glucagon; spontaneous remission may occur 3-12 months after surgery Treatment, medical Smaller meals, ↓ carbohydrate intake, pectin–a dietary fiber, acarbose, anticholinergics, l-dopa and opiates T˜reatment, surgical 2-5% are medical failures, requiring surgical conversion to a Roux-en-Y
Note: Other postgastrectomy syndromes include the small capacity, afferent and efferent loop syndromes, bile gastritis, anemia, postvagotomy diarrhea and metabolic bone disease  

dump·ing syn·drome

(dŭmp'ing sin'drōm)
A syndrome that occurs after eating, most often seen in patients with shunts of the upper alimentary canal; characterized by flushing, sweating, dizziness, weakness, and vasomotor collapse, occasionally with pain and headache; results from rapid passage of large amounts of food into the small intestine, with an osmotic effect removing fluid from plasma and causing hypovolemia.
Synonym(s): early dumping syndrome, postgastrectomy syndrome.