Ingenuity Pathway Analysis showed the following biological functions to be affected in the HPV+ samples: cancer, hematological disease, and RNA post-transcriptional modification
Of all the RNAs, tRNA exhibits the largest number and most diverse modifications with cells from all kingdoms of life allocating a large portion of their genome to encoding enzymes involved in the post-transcriptional modification
of nucleosides in tRNA .
Our comprehensive approach will answer how post-transcriptional modification
control stem cell fate in normal tissues and might lead to the discovery of novel therapeutic strategies for neurological disorders in humans.
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are complexes of RNA and protein present in the nucleus during gene transcription and subsequent post-transcriptional modification
of the newly synthesised RNA (pre-mRNA).
7) An alternative explanation for the low CK levels is that a generalised inflammatory state may result in post-transcriptional modification
and enhanced degradation of CK.
of proteins occur by all of the following EXCEPT