postinfectious glomerulonephritis

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postinfectious glomerulonephritis

the acute form of glomerulonephritis, which may follow 1 to 6 weeks after a streptococcal infection, most often in childhood. Characteristics of the disease are hematuria, oliguria, edema, and proteinuria, especially in the form of granular casts. There may be slight impairment of renal function in adults, but most patients recover fully in 1 to 3 months. There is no specific treatment for this form of glomerulonephritis. Restriction of dietary protein and the prescription of diuretics may be necessary until kidney function returns to normal. Also called acute glomerulonephritis. See also chronic glomerulonephritis, subacute glomerulonephritis.
observations Onset of symptoms occurs 1 to 6 weeks after a streptococcal infection. Symptoms include hypertension, headache, edema, oliguria, dark urine, reduced urine output, flank pain, weight gain, fever, chills, nausea, and vomiting; about half of cases are asymptomatic. Diagnosis is made through a series of lab tests. Hematuria (microscopic or gross), proteinuria, sediment, and RBC casts are seen on urinalysis. Blood chemistries reveal increased blood urea nitrogen, increased serum creatinine, increased serum lipids, and decreased serum albumin. ASO titers are positive. Complications include congestive heart failure, acute or chronic renal failure, and end-stage renal disease.
interventions Treatment focuses on treating symptoms and preventing complications. Antihypertensives are administered for hypertension, diuretics are given for edema, and antiinfective drugs are administered if an infection is still present. Electrolytes are monitored and abnormalities corrected. Diet therapy focuses on restricted sodium, restricted potassium, and low protein to combat electrolyte abnormalities and uremia. Hemodialysis or peritoneal dialysis may be used to treat renal failure.
nursing considerations Nursing management in acute care focuses on supportive measures. Bed rest, fluid, and electrolyte restrictions and dietary reduction of protein are necessary until signs of inflammation (e.g., proteinuria and hematuria) subside. Instruction centers on restrictions and proper administration of a full course of antibiotics. Prevention is also key and involves encouraging individuals to seek early diagnosis and treatment of sore throats and skin lesions, particularly in children.
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Postinfectious glomerulonephritis: red blood cell cast
References in periodicals archive ?
7%), including pneumonia in 5, tonsillitis in 2, ascites in 2, severe anaemia in 1, post-streptococcal glomerulonephritis in 1 and cerebrovascular accident in 1.
28] One child in the present study was noted to have concurrent ARF and post-streptococcal glomerulonephritis, an unusual occurrence that is thought to be due to some GAS strains being both nephritogenic and rheumatogenic.
Acute post-streptococcal glomerulonephritis (APSGN) is a non-suppurative, immunologically mediated complication of group A beta-haemolytic streptococcal infections.
Polymorphism ofthe streptokinase gene: implications for the pathogenesis of post-streptococcal glomerulonephritis.
Post-streptococcal glomerulonephritis, which is a kidney inflammation that may lead to chronic kidney failure.
An epidemic of acute post-streptococcal glomerulonephritis among Aboriginal children.
In addition to being a prevalent pathogen in sore throats, GAS is also responsible for sequelae such as rheumatic fever and post-streptococcal glomerulonephritis.
Acute post-streptococcal glomerulonephritis usually develops 10 - 14 days after a skin or throat infection with a nephritogenic strain of group A streptococcus.
However, untreated strep throat can result in the spread of infection to other vital organs, scarlet fever, rheumatic fever and post-streptococcal glomerulonephritis (inflammation of the kidneys).
In addition, infections with group A streptococci can trigger a variety of serious "post-streptococcal diseases," including rheumatic fever, post-streptococcal glomerulonephritis (a form of kidney disease), and neurologic abnormalities.
Serious complications of GAS infection include rheumatic fever and acute post-streptococcal glomerulonephritis.

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