Porter-Silber reaction

Por·ter-Sil·ber re·ac·tion

(pōr'tĕr sil'bĕr),
the basis of the 17-hydroxycorticosteroid test; C-21 adrenocorticosteroids, which contain a dihydroxyacetone group at carbons 19, 20, and 21, react with phenylhydrazine.

Porter-Silber reaction

Etymology: Curt C. Porter, American biochemist, b. 1914; Robert H. Silber, American biochemist, b. 1915
a reaction, visible as a change in color to yellow, that indicates the amount of adrenal steroids (the 17-hydroxycorticosteroids) excreted per day in the urine. The test is used to evaluate adrenocortical function but is now largely supplanted by immunoassay techniques.

Porter,

Curt C., U.S. biochemist, 1914–.
Porter-Silber chromogens - used chiefly to determine plasma cortisol concentrations and the urinary output of 17-hydroxycorticoids.
Porter-Silber chromogens test - a urine test used as a measure of adrenocortical function. Synonym(s): 17-hydroxycorticosteroid test
Porter-Silber reaction - the basis of the 17-hydroxycorticosteroid test.

Silber,

Robert H., U.S. biochemist, 1915–.
Porter-Silber chromogens - see under Porter, Curt C
Porter-Silber chromogens test - see under Porter, Curt C
Porter-Silber reaction - see under Porter, Curt C