Erdheim-Chester disease

(redirected from Polyostotic sclerosing histiocytosis)

Erd·heim-Chester disease

(erd'hīm-ches'tĕr),
rare systemic disorder characterized by proliferation of histocytes, by symmetric sclerosis at diametaphysial portions of lower limbs, and by extraskeletal involvement. Microscopically, infiltration of affected organs by lipophages and Touton giant cells is evident.
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