polyomavirus


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

Pol·y·o·ma·vi·rus

(pol'ē-ō'mă-vī'rŭs),
A genus of viruses (family Papovaviridae) containing DNA (MW 3 × 106), having virions about 45 nm in diameter, and including viruses oncogenic for animals; includes the polyoma virus of rodents, vacuolating viruses (SV40) of primates, and the BK and JC viruses of humans.
[poly- + G. -ōma, tumor]

polyomavirus

/poly·o·ma·vi·rus/ any member of the subfamily Polyomavirinae.

Polyomavirus

/Poly·o·ma·vi·rus/ (-vi″rus) polyomaviruses; a genus of viruses of the subfamily Polyomavirinae (family Papovaviridae) that induce tumors in experimental animals; two, BK virus and JC virus, infect humans, and others, including simian virus 40 (SV40), infect other mammals.

polyomavirus

(pŏl′ē-ō′mə-vī′rəs)
n.
Any of a genus of DNA viruses that infect birds and mammals and induce tumors in certain rodents.

polyomavirus

A small icosahedral, double-stranded oncogenic DNA virus of the Papovaviridae family, which may be used to induce experimental tumours in mice. The polyomavirus may be identified in both domestic and wild rodents.

Pol·y·o·ma·vi·rus

(pol'ē-ō'mă-vī'rŭs)
A genus of viruses oncogenic for animals; includes the polyoma virus of rodents, and the BK and JC viruses of humans.
[poly- + G. -ōma, tumor]

Polyomavirus

a genus in the family Papovaviridae that includes simian virus 40 and polyomavirus, both of which cause tumors in rodents and have been extensively studied as models of oncogenic DNA viruses. A polyoma-like virus may cause an acute disease in psittacine birds.
References in periodicals archive ?
Re: clinical factors associated with Merkel cell polyomavirus infection in Merkel cell carcinoma.
Molecular epidemiology of human polyomavirus JC in the Biaka pygmies and Bantu of Central Africa.
Prospective monitoring of BK polyomavirus infection early post-transplantation in nonrenal solid organ transplant recipients.
Polyomavirus BK-specific cellular immune response to VP1 and large T-antigen in kidney transplant recipients.
Busam KJ, Jungbluth AA, Rekthman N, et al: Merkel cell polyomavirus expression in merkel cell carcinomas and its absence in combined tumors and pulmonary neuroendocrine carcinomas.
The recently discovered Merkel cell polyomavirus (MCPyV) harboured in the inflammatory monocytes is said to be implicated in the oncogenesis of Merkel cell carcinoma (MCC).
STRATIFY JCV is the first blood test to receive FDA marketing authorisation for the detection of antibodies to the polyomavirus JC virus (JCV) for stratifying risk for progressive multifocal leukoencephalopathy (PML).
Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblasts.
A recent study showed that patients with Merkel cell polyomavirus (MCV) positive MCC had a better overall survival than patients with MCV negative MCC (5).