polyglandular autoimmune syndrome


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polyglandular autoimmune syndrome

Either of 2, often overlapping endocrinopathies, characterized by gonadal failure, possibly 2º to hypothalamic defects with vitiligo and autoimmune adrenal insufficiency–80% have autoantibodies. Types: Type I APECED An AR  condition of late childhood onset with hypoparathyroidism, mucocutaneous candidiasis, alopecia, pernicious anemia, malabsorption, chronic hepatitis;  Type II Schmidt syndrome An AR condition of adult onset with Addison's disease, and autoimmune (Hashimoto's) thyroiditis and/or IDDM

polyglandular autoimmune syndrome

Any of several syndromes that combine endocrine and autoimmune disorders. Synonym: autoimmune endocrine failure syndrome; autoimmune polyglandular syndrome; polyendocrine deficiency syndrome

type 1 polyglandular autoimmune syndrome

A polyglandular autoimmune syndrome that begins at about age 12 and is characterized by hypoparathyroidism, primary adrenal insufficiency, and mucocutaneous candidiasis. Alopecia, pernicious anemia, malabsorption, and chronic hepatitis may also be present.

type 2 polyglandular autoimmune syndrome

Schmidt syndrome.

Schmidt,

Adolph, German physician, 1865-1918.
Schmidt diet - used to subsequently examine diarrheic stools.
Schmidt syndrome - one-sided paralysis caused by a lesion of the nucleus ambiguus and the nucleus accessorius. Synonym(s): polyglandular autoimmune syndrome

Patient discussion about polyglandular autoimmune syndrome

Q. My boy has diabetes. Recently he was diagnosed with vitiligo. What is it and what can be the reason for this? My boy has diabetes. recently he was diagnosed with vitiligo. Our doctor said that he hopes it not a polyglandular autoimmune syndrome. what is vitiligo and what does this big phrase (polyglandular autoimmune syndrome) mean?

A. Vitiligo is a pigmentation disorder and the major cause of vitiligo is the autoimmunity. Some internal factor cause the destruction of melanocytes cell which produce the melanin a substance responsible for the coloration of skin. this lack of melanin infect results in <a href="http://www.antivitiligo.com/">white patch on skin</a> of hypo pigmentation.
Normally vitiligo is not related with other disease like diabetes. However a little inheritance may include in the occurence of vitiligo.

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