polyene antibiotic

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polyene antibiotic

A broad-spectrum antifungal produced by Streptomyces spp, eg amphotericin B, nystatin, pimaricin; toxicity may be ameliorated by newer drug delivery systems–eg, liposomes, lipid dispersions, colloidal suspensions
References in periodicals archive ?
While high-dose amphotericin B intravenously is the first-line therapy in systemic fusarioses, polyene antimycotics are probably not beneficial against infections caused by N.