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polyadenylation
(redirected from Poly-A tail)

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polyadenylation
the addition of up to 250 adenylate residues to the 3′ end of eukaryotic mRNAs to form a so-called poly(A) tail. The primary transcript is cleaved by a specific endonuclease that recognizes the sequence AAUAAA which is also referred to as a polyadenylation signal sequence. The poly(A) tail protects the mRNA from digestion with nuclease and greatly increases the efficiency of translation.
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The sequence (3381 nt) from the 3' end of open reading frame 1 (ORF 1) to the poly-A tail of the CaCV (strain 170/07) was made available in GenBank (accession no.
Detection and molecular characterization of a canine norovirus by Martella, Vito; Lorusso, Eleonora; Decaro, Niccola; Ella, Gabriella; Radogna, Arianna; D'Abramo, Mar / Emerging Infectious Diseases
The sequence of the 3' end of open reading frame (ORF)1, the full-length ORF2, ORF3, and the noncoding region through the poly-A tail was determined (GenBank accession no.
Norovirus in captive lion cub (Panthera leo) by Buonavoglia, Canio / Emerging Infectious Diseases
Whole Transcript Amplification effectively initiates the process from anywhere along the mRNA without the need for a Poly-A tail.
NuGEN Announces Launch of WT-Ovation(TM) RNA Amplification System; ... by Business Wire
 
 
 
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