Table 1: Composition of Drug Coating Solution Material Weight % Paclitaxel 33 % Poly Lactide-co-Glycolide 60% Poly Vinyl Pyrrolidone
7% Table 2: Degradation Rate Constant and Half- life Data Phase I II Time 0-15 16-90 Degradation Rate 0.
Two Biodegradable polymers-50/50 Poly DL Lactide-co-Glycolide (50/50 PLGA) and Poly vinyl pyrrolidone (PVP)-were dissolved in HPLC grade dichloromethane (DCM) and crystal violet dye was added in this solution.
61% Table 2: Formulation containing Sirolimus drug and polymers Material Name % in Formulation 1 Sirolimus 40% 2 50/50 Poly DL 56% Lactide-co-Glycolide 3 Poly vinyl pyrrolidone 4%
Biodegradable polymers; 65/35 Poly DL lactideco-glycolide, 85/15 Poly L lactide-cocaprolactone, Poly L-lactide and Poly vinyl pyrrolidone were dissolved in HPLC grade dichloromethane.
After immersion of stents in PBS, layer D dissolves rapidly as poly vinyl pyrrolidone is highly hydrophilic in nature.