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polyadenylation
(redirected from Poly A)

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
polyadenylation
the addition of up to 250 adenylate residues to the 3′ end of eukaryotic mRNAs to form a so-called poly(A) tail. The primary transcript is cleaved by a specific endonuclease that recognizes the sequence AAUAAA which is also referred to as a polyadenylation signal sequence. The poly(A) tail protects the mRNA from digestion with nuclease and greatly increases the efficiency of translation.


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Mr Smith joined Lunn Poly as a trainee manager in 1974 and went on to become managing director, leading the company to market leadership in the UK and increasing its chain of shops from 500 to 800 during his 10 years at the top.
And it's the double-stranded RNA, in various combinations (poly I poly C, poly A poly U and others), that is the key to the immune system-enhancing effects of these biological response modifiers.
Dennis ran 11 yards untouched for the game-winning touchdown with 8:38 left, giving Poly a 28-21 lead.
 
 
 
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