Pneumocystis ca·ri·ni·i (k -r  n - )n. A parasite transitional between a fungus and protozoan, frequently occurring as aggregate forms existing within rounded cystlike structures. It is the causative agent of pneumocystosis. |
Pneumocystis
a genus of organisms of uncertain status, but considered to be protozoa.
Pneumocystis carinii
the causative agent of interstitial plasma cell pneumonia in humans and immunocompromised Arab foals and dogs.
Pneumocystis carinii
Pneumocystosis Infectious disease An opportunistic 'bug' causing pneumonia–PCP in immunocompromised hosts–eg, with AIDS, leukemia, lymphoma, organ transplants, corticosteroid therapy, cytotoxic
drugs, the elderly Diagnosis GMS staining of tissues; P carinii also causes otic infection and choroiditis Prophylaxis In advanced HIV infection, aerosolized pentamidine, T-S, and high-dose dapsone are equally effective; the latter 2 are
superior in Pts with < 100 CD4+/mm3 Treatment T-S, manipulation of inflammatory response, and immune enhancement pentamidine, atovaquone, trimetrexate glucuronate
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