pleiotropy

(redirected from Pleiotrophy)
Also found in: Dictionary, Encyclopedia.
Related to Pleiotrophy: epistasis, pleiotropism

pleiotropy

 [pli-ot´rŏ-pe]
the production by a single gene of multiple phenotypic effects. The term is often used to refer to a single gene defect that is expressed as problems in multiple systems of the body, such as in osteogenesis imperfecta, where the gene causes defects in several different systems that contain collagen.

plei·ot·ro·py

, pleiotropia (plī-ot'rō-pē, plī-ō-trō'pē-ă),
Production by a single mutant gene of apparently unrelated multiple effects at the clinical or phenotypic level.
[pleio- + G. tropos, turning]

pleiotropy

/plei·ot·ro·py/ (-pe) the production by a single gene of multiple phenotypic effects.pleiotrop´ic

pleiotropy

(plī-ŏt′rə-pē) also

pleiotropism

(-pĭz′əm)
n. Biology
The production of diverse effects, especially the production by a single gene of several distinct and seemingly unrelated phenotypic effects.

plei′o·tro′pic (plī′ə-trō′pĭk, -trŏp′ĭk) adj.

pleiotropy

[plī·ot′rəpē]
Etymology: Gk, pleion, more, trepein to turn
the production by a single gene of a complex of unrelated phenotypic effects. The effects may be a manifestation of a particular disorder, such as the cluster of symptoms in Marfan's syndrome; aortic aneurysm; dislocation of the optic lens; skeletal deformities; and arachnodactyly, any or all of which may be present. pleiotropic, adj.

plei·ot·ro·py

, pleiotropia (plī-ot'rŏ-pē, -ō-trō'pē-ă)
Production by a single mutant gene of apparently unrelated multiple effects at the clinical or phenotypic level.
[pleio- + G. tropos, turning]

pleiotropism, pleiotropy

the production by a single gene of multiple phenotypic effects.