Platelets


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Related to Platelets: Neutrophils, low platelets, White blood cells

platelets

[plat′lits]
Etymology: Fr, small plate
anucleate blood cells, 1-3 μm in diameter. Platelets are formed from bone marrow megakaryocytes. Approximately one third of circulating platelets become temporarily sequestered in the spleen. Platelets are disk-shaped, contain no hemoglobin, and are essential for coagulation and in maintenance of hemostasis. The platelet count reference interval is 150,000-450,000/uL. Also called thrombocyte. Compare erythrocyte, leukocyte. See also thrombocytopenia, thrombocytosis.
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Platelets

blood platelets

or

platelets

or

thrombocytes

disc-like components of mammalian BLOOD, consisting of non-nucleated cytoplasmic fragments of large bone-marrow cells 3 μm in diameter called megakaryocytes that have entered the blood circulatory system. Platelets play an important part in BLOOD CLOTTING.

Platelets

Fragments of a large precursor cell (a megakaryocyte) found in the bone marrow. These fragments adhere to areas of blood vessel damage and release chemical signals that direct the formation of a blood clot.

platelets

syn thrombocytes cellular fragments in the blood, involved in blood coagulation. Platelets aggregate and adhere to form a temporary plug at the site of blood vessel damage.
References in periodicals archive ?
Moreover, in the vast majority of subjects no request was made for measuring platelets or platelet parameters.
This holds true for both ways of expressing retPLTs: as a percentage of platelets and as absolute retPLT count.
In addition to cost, another factor that may have played a role in the culture of SDP use over pooled platelet use at BUMC was the belief among medical personnel that pooled platelets would result in a higher incidence of alloimmunization due to more donor exposures.
Another factor influencing the increased use of SDP over pooled platelets was likely fear of increased infection with pooled platelets.
This is most likely due to the fact that immature platelets (typically larger in size) are more reactive than their older counterparts.
Finally, the MPV can be used in the laboratory for improved detection of platelet morphologic abnormalities such as giant platelets and platelet clumps--critical abnormalities that can cause platelets to be misinterpreted as WBCs and lead to erroneous results in the CBC.
2], released from platelets, is a strong mediator of platelet aggregation (Clemetson and Clemetson 2007; Surin et al.
Moreover, hericenone B inhibited collagen-induced aggregation in human platelets in a concentration-dependent manner with an [IC.
Flow cytometric studies in whole blood show increased platelet surface expression of P-selectin, increased binding of thrombospondin to platelets and increased amounts of platelet-leukocyte aggregates in MPN patients compared to controls (22), (23).
However, interpretations get complicated when taking into account results obtained from analyses that activate platelets in vitro.
Even if all the COX-1 is inactivated, platelets will still respond to higher concentrations of other agonists through separate pathways involving adenylcyclase or PLC (Figure 1).
However, they still cannot prevent the activation of platelets by higher concentrations of agonists acting through PLC.