Plasmodium falciparum


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Related to Plasmodium falciparum: Plasmodium ovale, Plasmodium malariae

Plas·mo·di·um fal·cip·a·rum

Laverania falcipara, a species that is the causal agent of falciparum (malignant tertian) malaria; a young trophozoite is about one fifth the size of an erythrocyte, but developing erythrocytic stages are rarely seen in circulating blood, because they render infected cells sticky and cause them to concentrate in capillaries in the vital organs, particularly the brain and the heart; a schizont occupies about one half to two thirds of the erythrocyte and has fine, sparse granules (observed in peripheral blood only from moribund patients); infected erythrocytes are normal or contracted in size and are likely to contain basophilic granules and red dots (Maurer clefts or dots); multiple infection is extremely frequent, which causes bouts of fever somewhat irregularly, bcause the parasite's cycles of multiplication are usually asynchronous.

Plas·mo·di·um fal·cip·a·rum

(plaz-mōdē-ŭm falsi-pārŭm)
Laverania falciparum, a protozoal species that is the causal agent of falciparum (malignant tertian) malaria; the species is not selective, infecting erythrocytes regardless of whether they are mature or immature or whether they are of normal, large, or contracted size; infected erythrocytes are likely to contain basophilic granules and red dots (Maurer clefts or dots); multiple infection is extremely frequent and causes bouts of fever somewhat irregularly because the parasites' cycles of multiplication are usually asynchronous.

Plasmodium falciparum

The causative agent of malignant (falciparum) malaria.
See also: Plasmodium

Plas·mo·di·um fal·cip·a·rum

(plaz-mōdē-ŭm falsi-pārŭm)
Laverania falcipara, a species that is the causal agent of falciparum (malignant tertian) malaria.
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A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study.
iii) Test was considered to be mixed infection if one line appear in the control region, one in the plasmodium falciparum region and one in the pan malarial region.
The heterozygous genotype showed no significant effect in modulating the probability of acquisition of malaria caused by Plasmodium falciparum (OR: 1.
Clinical immunity to Plasmodium falciparum malaria is associated with serum antibodies to the 19-kDa C-terminal fragment of the merozoite surface antigen, PfMSP-1.
The Plasmodium Falciparum infection was more predominant (n=48) as the area is more endemic.
Efficacy and tolerability of artesunate plus sulfadoxine-pyrimethamine and sulfadoxine-py rimethamine alone for the treatment of uncomplicated Plasmodium falciparum malaria in Peru.
Longitudinal surveillance of in vitro pyrimethamine resistance in Plasmodium falciparum.
Plasmodium vivax is more frequent than Plasmodium falciparum.
Amongst the four species of Plasmodium that transmit human malaria, Plasmodium falciparum is responsible forthe most severe clinical manifestations of disease and causes most malaria morbidity and almost all malaria mortality [3].
This new target comes in addition to the original 2006 Roadmap's goal of having a licensed vaccine against Plasmodium falciparum malaria, the most deadly form of the disease, for children under 5 years of age in sub-Saharan Africa by 2015.

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