PiZZ


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PiZZ

The most common variant allele in α1-antitrypsin deficiency; the common normal allele is PiMM. See α1-antitrypsin deficiency.
References in periodicals archive ?
In a Danish study on never-smoking non-index cases of phenotype PiZZ, no abnormalities in lung function could be identified (Seersholm et al.
Indications: For long-term augmentation therapy in patients with Alpha(1)-proteinase inhibitor deficiency (genotype PiZZ, PiZ-Null, PiNull-Null, and PiSZ) within the limits of moderate airflow obstruction (FEV1 35-60%) and the evaluation of the clinical condition (disability).
Equally obvious were a bunch of on pointers such as Blacknails, Pizz, Josh Agle, Bondo Bob Wins and Big Daddy "Ed" Riggins.
The 2D-PAGE analysis of PIZZ patient plasma showed changes in the intensity and pI of all the [[alpha].