Printer Friendly
Dictionary, Encyclopedia and Thesaurus - The Free Dictionary
3,902,560,151 visitors served.
forum Join the Word of the Day Mailing List For webmasters
?
Dictionary/
thesaurus
Medical
dictionary
Legal
dictionary
Financial
dictionary
Acronyms
 
Idioms
Encyclopedia
Wikipedia
encyclopedia
?

hypothalamic-pituitary-adrenal axis
(redirected from Pituitary-adrenal axis)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
hypothalamic-pituitary-adrenal axis,
the combined system of neuroendocrine units that in a negative feedback network regulate the adrenal gland's hormonal activities.

hypothalamic-pituitary-adrenal axis
A tightly-linked, interdependent endocrine unit which, with the systemic sympathetic and adrenomedullary systems, comprises a major peripheral limb of the stress system, the main function of which is to maintain basal and stress-related homeostasis; the hypothalamus and pituitary form the central part of the HPA axis, and are active even at rest, responding to blood-borne or neurosensory signals–eg, cytokines–eg, IL-1, IL-6, TNF-α; at the highest level, CRH and noradrenergic neurons innervate and stimulate each other, which is controlled by an autoregulatory, ultrashort negative-feedback loop, in which CRH and noradrenergic collateral fibers inhibit presynaptic CRH and α2-noradrenergic receptors. Cf Hypothalamic-pituitary axis.


Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
?Page tools
Printer friendly
Cite / link
Feedback
Add definition
Mentioned in?  References in periodicals archive?   Medical browser?   Full browser?
 
Chronic use of this drug can be associated with some increased risk for developing diabetes mellitus, Cushing's syndrome, and suppression of the pituitary-adrenal axis.
The abnormalities reflect the activation of the pituitary-adrenal axis, said Dr.
 
 
 
Medical Dictionary
?

Terms of Use | Privacy policy | Feedback | Advertise with Us | Copyright © 2012 Farlex, Inc.
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.