piperazine

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piperazine

 [pi-per´ah-zēn]
an anthelmintic used in various salts against Ascaris lumbricoides and Enterobius vermicularis.

pi·per·a·zine

(pī-per'ă-zēn, -zin),
A veterinary anthelmintic and filaricide.
Synonym(s): diethylenediamine

piperazine

/pi·per·a·zine/ (-zēn) an anthelmintic used against Ascaris lumbricoides and Enterobius vermicularis; used as the citrate salt.

piperazine

(pī-pĕr′ə-zēn′, pĭ-)
n.
1. An organic compound, C4H10N2, that is used (often in the form of a salt) as an anthelmintic in humans and domestic animals and is widely used in the manufacture of pharmaceuticals, synthetic resins, polyurethane, and other industrial products.
2. Any of various derivatives of this compound, some of which have stimulant and hallucinogenic properties.

piperazine

An ANTHELMINTIC drug used to get rid of ROUNDWORMS and THREADWORMS. The drug paralyses the worms which are then passed with the faeces. A brand name for the drug formulated with the laxative senna is Pripsen.

pi·per·a·zine

(pī-per'ă-zēn, -zin)
A veterinary anthelmintic and filaricide.
Synonym(s): diethylenediamine.

piperazine (piper´əzēn),

n an anthelmintic agent that acts against the roundworm
Ascaris lumbricoides and the pinworm
Enterobius vermicularis by interfering with their nerve transmissions, thereby causing paralysis.

piperazine

an anthelmintic; several of its salts are used, especially in horses and dogs. A useful agent especially against ascarids. Combined with a benzimidazole is effective against Parascaris equorum and benzimidazole-resistant small strongyles.
Piperazine is a very safe medicament but poisoning occurs on doses that are several times normal. Signs include incoordination, pupillary dilatation, hyperesthesia, somnolence, tremor, swaying at rest and recumbency. Spontaneous recovery usual.
References in periodicals archive ?
The piperazine series has been shown in both cell based and small animal model anti-cancer studies performed by the National Cancer Institute (NCI, USA) and Samjin, to have significant and diverse biological anti-tumor activities.
We are quite pleased to extend our drug development alliance with Samjin to include these unique and completely new class of piperazine anti-cancer agents," said Robert W.
Classical synthetic routes to the unsymmetrically N,N'-diarylated piperazine moiety 1 encompass the reaction of anilines with bis(2-chloroethyl)amine directly (K.
Cinnarizine is a piperazine that exerts calcium channel blocking effects.
These compounds include methoxetamine (an analog to ketamine), kratom (a compound derived from Mitragyna speciosa) and piperazine (an antihelminthic that has been shown to produce amphetamine-like effects).