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The protein component of bacterial adhesive appendages that help the bacterium to stick to tissue or container surfaces, often the glycoproteins on the surface of eukaryotic cells.
[pilus 2. + -in]
References in periodicals archive ?
This arrangement of constant and variable pilin sequences is reminiscent of that of immunoglobulin [antibody] gene segments," the scientists say in the April PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (No.
Therefore a bacterium with pili can be the progenitor to bacteria with different pilin proteins.
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influenzae type b pilin (hif), but could find no systematic difference in binding of HaeBPF and conventional Hae strains to human epithelial cells and could not conclusively implicate this locus in virulence.
Furthermore, by using specific antibodies directed against the major pilin subunits (16,17), we identified a clear, nonrandom association between ST28 strains and expression of both pili (Table 3).
Mutations in the gene encoding the ancillary pilin subunit of the Streptococcus suis srtF cluster result in pili formed by the major subunit only.
Although the authors define aEPEC strictly on the basis of positivity for the LEE eae gene and failure to amplify a bfpA pilin gene (not assessing additional plasmid loci), the absence of tEPEC serotypes and the occurrence of disease in children older than infants suggest that these are indeed aEPEC.
These strains possess a novel bfpA allele encoding the type IV pilin characteristic of typical enteropathogenic E.
The subgroup III strains uniformly expressed the class I and IIa pilin epitopes (8); however, the pilin epitopes of subgroups VI and X were not uniform: half of each group of strains expressed class I and IIa epitopes and the other half the class IIb epitope.