photodynamic therapy

therapy /ther·a·py/ (-pe) the treatment of disease; see also treatment.

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ablation therapy  the destruction of small areas of myocardial tissue, usually by application of electrical or chemical energy, in the treatment of some tachyarrhythmias.

adjuvant therapy  the use of chemotherapy or radiotherapy in addition to surgical resection in the treatment of cancer.

antiplatelet therapy  the use of platelet-modifying agents to inhibit platelet adhesion or aggregation and so prevent thrombosis, alter the course of atherosclerosis, or prolong vascular graft patency.

art therapy  the use of art, the creative process, and patient response to the products created for the treatment of psychiatric and psychologic conditions and for rehabilitation.

aversion therapy , aversive therapy that using aversive conditioning to reduce or eliminate undesirable behavior or symptoms; sometimes used synonymously with aversive conditioning.

behavior therapy  a therapeutic approach that focuses on modifying the patient's observable behavior, rather than on the conflicts and unconscious processes presumed to underlie the behavior.

biological therapy  treatment of disease by injection of substances that produce a biological reaction in the organism.

chelation therapy  the use of a chelating agent to remove toxic metals from the body, used in the treatment of heavy metal poisoning. In complementary medicine, also used for the treatment of atherosclerosis and other disorders.

cognitive therapy , cognitive-behavioral therapy that based on the theory that emotional problems result from distorted attitudes and ways of thinking that can be corrected, the therapist guiding the patient to do so.

convulsive therapy  treatment of mental disorders, primarily depression, by induction of convulsions; now it is virtually always by electric shock (electroconvulsive t.) .

couples therapy  marital t.

dance therapy  the therapeutic use of movement to further the emotional, social, cognitive, and physical integration of the individual in the treatment of a variety of social, emotional, cognitive, and physical disorders.

electroconvulsive therapy  (ECT) a treatment for mental disorders, primarily depression, in which convulsions and loss of consciousness are induced by application of brief pulses of low-voltage alternating current to the brain via scalp electrodes.

electroshock therapy  (EST) electroconvulsive t.

endocrine therapy  treatment of disease by the use of hormones.

estrogen replacement therapy  administration of an estrogen to treat estrogen deficiency, as that following menopause; in women with a uterus, a progestational agent is usually included to prevent endometrial hyperplasia.

enzyme therapy  in complementary medicine, the oral administration of proteolytic enzymes to improve immune system function; used for a wide variety of disorders and as adjunctive therapy in cancer treatment.

family therapy  group therapy of the members of a family, exploring and improving family relationships and processes and thus the mental health of the collective unit and of individual members.

fibrinolytic therapy  the use of fibrinolytic agents (e.g., prourokinase) to lyse thrombi in patients with acute peripheral arterial occlusion, deep venous thrombosis, pulmonary embolism, or acute myocardial infarction.

gene therapy  manipulation of the genome of an individual to prevent, mask, or lessen the effects of a genetic disorder.

group therapy  psychotherapy carried out regularly with a group of patients under the guidance of a group leader, usually a therapist.

highly active antiretroviral therapy  (HAART) the aggressive use of extremely potent antiretroviral agents in the treatment of human immunodeficiency virus infection.

hormonal therapy , hormone therapy endocrine t.

hormone replacement therapy  the administration of hormones to correct a deficiency, such as postmenopausal estrogen replacement ttherapy.

immunosuppressive therapy  treatment with agents, such as x-rays, corticosteroids, or cytotoxic chemicals, that suppress the immune response to antigen(s); used in conditions such as organ transplantation, autoimmune disease, allergy, multiple myeloma, and chronic nephritis.

inhalation therapy  former name for respiratory care (2).

light therapy 

1. phototherapy (def. 1).

2. photodynamic t.

marital therapy  a type of family therapy aimed at understanding and treating one or both members of a couple in the context of a distressed relationship, but not necessarily addressing the discordant relationship itself; sometimes used more restrictively as a synonym of marriage therapy .

marriage therapy  a subset of marital therapy (q.v.) that focuses specifically on the bond of marriage between two people, enhancing and preserving it.

massage therapy  the manipulation of the soft tissues of the body for the purpose of normalizing them, thereby enhancing health and healing.

milieu therapy  treatment, usually in a psychiatric hospital, that emphasizes the provision of an environment and activities appropriate to the patient's emotional and interpersonal needs.

music therapy  the use of music to effect positive changes in the psychological, physical, cognitive, or social functioning of individuals with health or educational problems.

occupational therapy  the therapeutic use of self-care, work, and play activities to increase function, enhance development, and prevent disabilities.

oral rehydration therapy  (ORT) oral administration of a solution of electrolytes and carbohydrates in the treatment of dehydration.

orthomolecular therapy  treatment of disease based on the theory that restoration of optimal concentrations of substances normally present in the body, such as vitamins, trace elements, and amino acids, will effect a cure.

photodynamic therapy  intravenous administration of hematoporphyrin derivative, which concentrates selectively in metabolically active tumor tissue, followed by exposure of the tumor tissue to red laser light to produce cytotoxic free radicals that destroy hematoporphyrin-containing tissue.

physical therapy 

1. treatment by physical means.

2. the health profession concerned with the promotion of health, the prevention of disability, and the evaluation and rehabilitation of patients disabled by pain, disease, or injury, and with treatment by physical therapeutic measures as opposed to medical, surgical, or radiologic measures.

poetry therapy  a form of bibliotherapy in which a selected poem, which may be created by the patient, is used to evoke feelings and responses for discussion in a therapeutic setting.

PUVA therapy  a form of photochemotherapy for skin disorders such as psoriasis and vitiligo; oral psoralen administration is followed two hours later by exposure to ultraviolet light.

radiation therapy  radiotherapy.

relaxation therapy  any of a number of techniques for inducing the relaxation response, used for the reduction of stress; useful in the management of a wide variety of chronic illnesses caused or exacerbated by stress.

replacement therapy 

1. treatment to replace deficiencies in body products by administration of natural or synthetic substitutes.

2. treatment that replaces or compensates for a nonfunctioning organ, e.g., hemodialysis.

respiratory therapy  see under care.

substitution therapy  the administration of a hormone to compensate for glandular deficiency.

thrombolytic therapy  fibrinolytic t.

thyroid replacement therapy  treatment with a preparation of a thyroid hormone.

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photodynamic therapy

n.

A type of phototherapy in which a nontoxic light-sensitive compound that has been injected into a patient is exposed selectively to light, whereupon it becomes toxic to targeted malignant and other diseased cells.

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Photodynamic therapy

A novel mode of treatment that uses a combination of special light rays and drugs are used to destroy the cancerous cells. First, the drugs, which make cancerous cells more susceptible to the light rays, are introduced into the bladder. Then the light is shone on the bladder to kill the cells.

Mentioned in: Bladder Cancer

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photodynamic therapy.

See photochemotherapy.

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photodynamic

activated or made more powerful by light.

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photodynamic agent

a substance that is activated by light to cause damage to tissue. It may be exogenous and absorbed preformed from the environment, or endogenous in that it is formed within the body as an abnormal metabolite, e.g. porphyrins, or as a normal metabolite, e.g. phylloerythrin, and accumulate in tissues because of faulty excretion, e.g. in hepatic disease.

photodynamic therapy

the use of photodynamic agents in the treatment of disease.

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macular degeneration, age-related (ARMD, AMD)

A common, chronic degenerative condition found in a large percentage of elderly patients (and sometimes middle-aged ones) characterized by loss of central vision. There are two main forms of the condition: non-neovascular (dry, atrophic) AMD, which is the most common, and exudative (wet, neovascular) AMD in which the loss of vision is the most severe. The main features of dry AMD are the presence in the macular region of small, yellowish-white spots (hard drusen) and large, poorly defined, coalescing soft drusen, focal hyperpigmentation of the retinal pigment epithelium (RPE) and at a later stage geographic atrophy of the RPE and depigmentation exposing choroidal vessels. Visual acuity becomes markedly reduced, there is metamorphopsia and the condition usually becomes bilateral over several years. The condition is managed essentially by the use of low vision aids.Exudative AMD has a similar clinical picture initially but is followed by choroidal neovascularization (CNV), which gives rise to subretinal fluid, haemorrhages, exudation, RPE detachment and subretinal fibrosis in the macular region resulting in severe loss of central vision. If detected early (usually with an Amsler chart), treatment with laser photocoagulation will reduce the risk of further visual loss. Photodynamic therapy (PDT) is another method of reducing the risk of visual loss. It allows selective destruction of the choroidal neovascularization with minimal damage to the overlying retinal tissue. It consists of injecting a photosensitizing agent (e.g. verteporfin) that is taken up by the abnormal vessels and when activated by a laser light of a given wavelength (e.g. 689 nm) it damages and shrivels up the vessels. Recent drug therapies, such as the anti-VEGF ranibizumab and bevacizumab, which are injected intravitreally at regular intervals and designed to stop the leakage and the growth of blood vessels, not only reduce loss of vision but improve visual acuity in a significant percentage of cases of wet AMD. Syn. senile macular degeneration. See fluorescein angiography; disciform scar; drusen; macular dystrophy; lipofuscin; age-related maculopathy; oxidative stress; macular pigment; Kollner's rule; photostress test; VEGF.

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photodynamic therapy

Oncology The injection of a site-specific photosensitizer in the body which accumulates in rapidly dividing cells, activated by certain wavelengths of light to treat and diagnose CA–eg, in situ transitional cell CA of bladder and other proliferative disorders. See Phototherapy Ophthalmology A nonthermal process for ↑ local reactive O₂ species which mediate local cellular, vascular, and immunologic injury; RT is used for outpatient treatment of macular degeneration–characterized by choroidal neovascularization of retina. See Age-related macular degeneration.