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A key intermediate in the formation of cephalins; formed in liver and brain by phosphorylation of ethanolamine.
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Phosphocholine is a metabolic product from phosphatidylcholine that forms the typical cellular membrane bilayer structure with phosphorylethanolamine and other neutral lipids controlling membrane integrity.
Within these three types of LPS, further levels of heterogeneity also exist; for instance the number of KDO units in the core oligosaccharide may vary, so too may the degree of phosphorylation or phosphorylethanolamine derivatization.
For the present studies, limulin was purified to homogeneity from the plasma of Limulus by sequential affinity chromatography on phosphorylethanolamine (PE)-agarose and fetuin-Sepharose, a sialic acid affinity resin.

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