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an enzyme that catalyzes the hydrolysis of a lecithin to a lysolecithin by removing the 2-acyl group; also acts on other phospholipids by removing a fatty acid from the 2-position; this enzyme has an important role in prostaglandin and leukotriene biosynthesis.
Synonym(s): lecithinase A, phosphatidase, phosphatidolipase
YWHAZA gene on chromosome 8q23.1 that encodes an adapter protein which regulates a broad spectrum of general and specialised signalling pathways by binding to a large number of partners, usually by recognising a phosphoserine or phosphothreonine motif.
enzyme catalyzing the hydrolysis of the fatty acyl group esterified in the 2-position of a phospholipid. Key enzyme in the release of arachidonic acid from this position for subsequent conversion to the eicosanoid group of humoral agents.